What happens if I miss a dose (Actemra)?
Call your doctor for instructions if you miss an appointment for your tocilizumab injection.
What happens if I overdose (Actemra)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while receiving tocilizumab (Actemra)?
Do not receive a "live" vaccine while using tocilizumab, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you. Live vaccines include measles, mumps, rubella (MMR), oral polio, chickenpox (varicella), BCG (Bacillus Calmette and Guérin), and nasal flu vaccine.
Avoid being near people who are sick or have infections.
What other drugs will affect tocilizumab (Actemra)?
Tell your doctor about all other medications you use, especially:
- birth control pills;
- a blood thinner such as warfarin (Coumadin);
- cyclosporine (Gengraf, Neoral, Sandimmune);
- digoxin (digitalis, Lanoxin, Lanoxicaps);
- omeprazole (Prilosec);
- sirolimus (Rapamune) or tacrolimus (Prograf);
- theophylline (Elixophyllin, Theo-24, Uniphyl);
- abatacept (Orencia), adalimumab (Humira), anakinra (Kineret) certolizumab (Cimzia), etanercept (Enbrel), golimumab (Simponi), infliximab (Remicade), or rituximab (Rituxan);
- atorvastatin (Lipitor), lovastatin (Mevacor) and other cholesterol-lowering medications;
- seizure medication such as carbamazepine (Carbatrol, Tegretol), divalproex (Depakote), phenytoin (Dilantin), or valproic acid (Depakene);
- a heart rhythm medication such as disopyramide (Norpace), procainamide (Pronestyl), or quinidine (Quin-G);
- other drugs that weaken your immune system (such as cancer medicine or steroids); or
- any other pain or arthritis medications (both prescription and over-the-counter) including methotrexate (Rheumatrex), aspirin, or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), etodolac (Lodine), indomethacin (Indocin), meloxicam (Mobic), nabumetone (Relafen), piroxicam (Feldene), and others.
This list is not complete and many other drugs may interact with tocilizumab. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Where can I get more information?
Your doctor or pharmacist can provide more information about tocilizumab.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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