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Medications and Drugs

Brand Names: PBZ, PBZ-SR

Generic Name: tripelennamine (Pronunciation: tri pel EH na meen)

What is tripelennamine (PBZ, PBZ-SR)?

Tripelennamine is an antihistamine. Tripelennamine blocks the effects of the naturally occurring chemical histamine in the body.

Tripelennamine is used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.

Tripelennamine may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of tripelennamine (PBZ, PBZ-SR)?

Stop taking tripelennamine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take tripelennamine and talk to your doctor if you experience

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about tripelennamine (PBZ, PBZ-SR)?

Use caution when driving, operating machinery, or performing other hazardous activities. Tripelennamine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking tripelennamine.

Do not crush, chew, or break the sustained-release forms of tripelennamine. Swallow them whole. They are specially formulated to release slowly in the body.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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