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Medications and Drugs

Brand Names: Zymine

Generic Name: triprolidine (Pronunciation: trye PROE li deen)

What is triprolidine (Zymine)?

Triprolidine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Triprolidine is used to treat symptoms of seasonal allergy, such as sneezing, itching, watery eyes, and runny nose.

Triprolidine may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of triprolidine (Zymine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • feeling light-headed, fainting;
  • fast, pounding, or uneven heartbeat;
  • confusion, hallucinations, unusual thoughts or behavior;
  • severe dizziness, anxiety, restless feeling, or nervousness; or
  • urinating less than usual or not at all.

Keep using the medication and talk with your doctor if you have any of these less serious side effects:

  • blurred vision;
  • dry mouth, stuffy nose;
  • change in appetite;
  • nausea, stomach pain;
  • constipation, diarrhea;
  • dizziness, drowsiness;
  • problems with memory or concentration;
  • ringing in your ears; or
  • restless or excitability (especially in children).

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about triprolidine (Zymine)?

Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain type of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine such as diphenhydramine or chlorpheniramine.

Avoid drinking alcohol while you are taking this medication. It can add to drowsiness caused by triprolidine.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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