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Medications and Drugs

Brand Names: Tham

Generic Name: tromethamine (Pronunciation: troe METH a meen)

What is tromethamine (Tham)?

Tromethamine affects the balance of water and electrolytes in the body.

Tromethamine is used to treat metabolic acidosis (an electrolyte imbalance). Metabolic acidosis can have many causes. It often occurs after heart bypass surgery or cardiac arrest.

Tromethamine may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of tromethamine (Tham)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have any of these serious side effects:

  • swelling, rapid weight gain, feeling short of breath;
  • weak or shallow breathing;
  • pain, swelling, or skin changes where the medicine was injected;
  • fast heart rate; or
  • feeling like you might pass out.

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about tromethamine (Tham)?

You should not receive this medication if you have uremia (urea circulating in your blood), or if you are unable to urinate (such as due to kidney failure).

Before receiving tromethamine, tell your doctor if you are allergic to any drugs, or if you have asthma, kidney disease, or congestive heart failure.

Tell your caregivers right away if you have any swelling or rapid weight gain, shortness of breath, weak or shallow breathing, swelling or skin changes where the medicine was injected, fast heart rate, or feeling like you might pass out.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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