Medications and Drugs
Brand Names: Zolinza
Generic Name: vorinostat (Pronunciation: vor IN o stat)
What is vorinostat (Zolinza)?
Vorinostat is usually given after other treatments have been tried without successful treatment.
Vorinostat may also be used for purposes not listed in this medication guide.
What are the possible side effects of vorinostat (Zolinza)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using vorinostat and call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about vorinostat (Zolinza)?
You should not use this medication if you are allergic to vorinostat, or if you have severe liver disease.
Do not use vorinostat if you are pregnant. It could harm the unborn baby.
You should not breast-feed while you are using vorinostat.
Drink at least 2 liters of water each day to keep from getting dehydrated while you are taking vorinostat. Tell your doctor if you have severe vomiting or diarrhea during treatment.
Do not crush or open a vorinostat capsule. Swallow it whole. The medicine inside the capsule can be dangerous if it gets in your eyes, mouth, or nose, or on your skin. If this occurs, wash your skin with soap and water or rinse your eyes with water. Ask your doctor or pharmacist how to safely handle and dispose of a broken tablet or capsule.
You may need regular medical tests to be sure this medication is not causing harmful effects. Visit your doctor regularly.
Stop using vorinostat and call your doctor at once if you have chest pain, sudden cough, wheezing, rapid breathing, coughing up blood, swelling or warmth in one or both legs, fever, chills, mouth sores, easy bruising or bleeding, bloody or tarry tools, or severe vomiting or diarrhea.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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