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Medications and Drugs

Brand Names:

Generic Name: xylometazoline nasal (Pronunciation: zye loe me TAH zoe leen)

What is xylometazoline nasal ()?

Xylometazoline nasal is a decongestant. It works by constricting (shrinking) blood vessels (veins and arteries) in the body. The nasal formulation acts directly on the blood vessels in the nasal tissues. Constriction of the blood vessels in the nose and sinuses leads to a decrease in congestion.

Xylometazoline nasal is used to treat congestion associated with allergies, hay fever, sinus irritation, and the common cold.

Xylometazoline nasal may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of xylometazoline nasal ()?

If you experience any of the following serious side effects from this medication, stop using xylometazoline nasal and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • seizures;
  • unusual behavior or hallucinations; or
  • an irregular or fast heartbeat.

More commonly, you may experience some sneezing or nasal burning, stinging, dryness, or irritation. These side effects are usually mild and temporary.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about xylometazoline nasal ()?

Do not use xylometazoline nasal for longer than 3 to 5 days. Longer use could cause damage to the nasal tissue and lead to chronic congestion. If your symptoms do not improve, see your doctor.

Do not use this medication in larger doses or more often than is recommended. Too much xylometazoline nasal could be harmful. Xylometazoline nasal should not be used more often than two to three times a day (every 8 to 10 hours).

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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