Medications and Drugs
Brand Names: Prialt
Generic Name: ziconotide (Pronunciation: zye KON oh tide)
What is ziconotide (Prialt)?
Ziconotide is a non-narcotic pain reliever that works by blocking pain signals from the nerves to the brain.
Ziconotide is used to treat severe chronic pain in people who cannot use or do not respond to standard pain-relieving medications.
Ziconotide may also be used for other purposes not listed in this medication guide.
What are the possible side effects of ziconotide (Prialt)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about ziconotide (Prialt)?
Severe psychiatric symptoms and neurological impairment may occur during treatment with ziconotide. You should not receive ziconotide if you have a history of psychiatric illness or psychotic event.
You should not use this medication if you are allergic to ziconotide, or if you have an uncontrolled bleeding or blood clotting disorder.
Ziconotide must be given only as an intrathecal injection through an infusion pump and should not be injected directly into a vein or other part of the body. Your doctor, nurse, or other healthcare provider will give you this injection.
Your doctor may occasionally change your dose or infusion pump flow rate to make sure you get the best results from this medication.
Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Tell your doctor if you regularly use other medicines that make you sleepy. Ziconotide can add to sleepiness caused by these other medications.
Call your doctor at once if you have a serious side effect, especially fever, neck stiffness, seizure (convulsions), extreme drowsiness or tired feeling, confusion, disorientation, hallucinations, thoughts of hurting yourself, or decreased consciousness.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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