zoledronic acid (cont.)
What happens if I miss a dose (Reclast, Zometa)?
Call your doctor for instructions if you miss an appointment for your zoledronic acid injection.
What happens if I overdose (Reclast, Zometa)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include numbness or tingling in your hands and feet, muscle stiffness, spasms in the muscles of your face, uneven heartbeats, and wheezing or trouble breathing.
What should I avoid while receiving zoledronic acid (Reclast, Zometa)?
Avoid having any type of dental surgery while you are being treated with zoledronic acid. It may take longer than normal for you to recover.
What other drugs will affect zoledronic acid (Reclast, Zometa)?
Zoledronic acid can harm your kidneys. This effect is increased when you also use other medicines harmful to the kidneys. You may need dose adjustments or special tests if you have recently used:
- a diuretic (water pill);
- lithium (Eskalith, Lithobid);
- methotrexate (Rheumatrex, Trexall);
- pain or arthritis medicines such as aspirin (Anacin, Excedrin), acetaminophen (Tylenol), ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others;
- medicines used to treat ulcerative colitis, such as mesalamine (Pentasa) or sulfasalazine (Azulfidine);
- medicine used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune) or tacrolimus (Prograf);
- IV antibiotics such as amphotericin B (Amphotec, AmBisome, Abelcet), amikacin (Amikin), bacitracin (Baci IM), capreomycin (Capastat), gentamicin (Garamycin), kanamycin (Kantrex), streptomycin, or vancomycin (Vancocin, Vancoled);
- antiviral medicines such as adefovir (Hepsera), cidofovir (Vistide), or foscarnet (Foscavir); or
- cancer medicine such as aldesleukin (Proleukin), carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), streptozocin (Zanosar), or tretinoin (Vesanoid).
This list is not complete and other drugs may interact with zoledronic acid. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your doctor or pharmacist can provide more information about zoledronic acid.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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