An allergic reaction is caused by the body's immune system overreacting to the drug, which is viewed as a chemical "invader," or antigen. This overreaction is often called a hypersensitivity reaction.
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Drug eruptions can mimic a wide range of dermatoses. The morphologies are myriad and include morbilliform (most common, see Media file 1), urticarial, papulosquamous, pustular, and bullous. Medications can also cause pruritus and dysesthesia without an obvious eruption.
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