E. coli: Escherichia coli 0157:H7, E. coli 0157:H7 (cont.)
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E. coli 0157:H7 Prognosis
People with E. coli 0157:H7 infection usually (about 90%) have a self-limited disease and the outcome is excellent. However, the prognosis worsens with the development of complication(s). Good hydration lessens the chances of complications and improves the outcome.
Individuals who develop hemorrhagic diarrhea and are treated promptly have better outcomes with reduced hospitalization. Complications such as HUS and TTP have a wide range of prognosis from good to poor, depending on the overall health of the individual and how quickly the complications are diagnosed and treated. For example, some individuals can recover completely, but others may require IV fluids, plasma exchange, plasma infusion, or dialysis and may have end-organ failure (usually kidney failure) and neurologic problems. A few (about 10%) of TTP patients will die. Although infrequent, relatively healthy children and adults have died from E. coli 0157:H7 infections due to dehydration.
Bhupinder Anand, MD
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