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E. coli: Escherichia coli 0157:H7, E. coli 0157:H7 (cont.)

Other Enterohemorrhagic E. coli Strains (for example, 0145, 026:H11)

Most enterohemorrhagic E. coli (EHEC or STEC) infections were thought to be variants of strain 0157:H7, however, enterohemorrhagic serotypes are not limited to the 0157:H7 serotype. Apparently, many other serotypes such as 0145 can acquire the plasmid that is responsible for the synthesis of Shiga (Vero) toxin and thus can produce almost identical symptoms produced by 0157:H7 in infected humans. Consequently, these other E. coli serotypes can cause outbreaks of bloody diarrhea with hemorrhagic colitis that can become complicated by hemolytic uremia. In 2012, strain 0145 caused 18 infections and one infant death. Another strain, E. coli 0121 infected 19 persons in 2014; the strain produced a Shiga toxin. The source of the bacteria was raw clover sprouts.

These other E. coli serotypes produce essentially the same type of disease as 0157:H7 and are diagnosed and treated in the same manner. Consequently, the following sections use 0157:H7 as the prototypic EHEC. For all practical purposes, 0157:H7 represents all the other EHEC serotypes.

REFERENCES:

CDC.gov. Multistate Outbreak of Shiga Toxin-producing Escherichia coli O145 Infections.

CDC.gov. Escherichia coli O157:H7.

CDC.gov.. Recommendations for Diagnosis of Shiga Toxin--Producing Escherichia coli Infections by Clinical Laboratories.

MedscapeReference.com. Hemolytic Uremic Syndrome.

Kumarasamy, K.K. et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. The Lancet, published online Aug. 11, 2010. (NDM)

Pitout, J.D.D. The latest threat in the war on antimicrobial resistance. The Lancet, published online Aug. 11, 2010.

Textbookofbacteriology.net. Pathogenic E. coli.

U.S. Food and Drug Administration. BBB - Escherichia coli O157:H7 (EHEC).
 


Medically Reviewed by a Doctor on 4/28/2015
Medical Editor:

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