Medications

Medicines, such as chemotherapy, may be given after surgery for endometrial cancer, depending on the stage and grade of the cancer and the risk for the cancer to spread (metastasis) or recur. Progestin hormone therapy may be used if your cancer has recurred or spread or you are unable to have surgery or radiation therapy.

Medication Choices

Medicine treatment for endometrial cancer may include hormone therapy or chemotherapy.

Progestin hormone therapy. Examples include:

• Hydroxyprogesterone (Delalutin).
• Megestrol (Megace).
• Medroxyprogesterone (Provera).

Chemotherapy, used alone or in combination. Examples include:

• Doxorubicin.
• Cisplatin.
• Paclitaxel.
• Carboplatin.
• Topotecan.

Nausea and vomiting are common side effects of chemotherapy. These side effects usually are temporary and go away when treatment is stopped. Your doctor will prescribe medicines to help relieve nausea. These medicines include serotonin antagonists, phenothiazines, and aprepitant.