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Enlarged Prostate (Benign Prostatic Hyperplasia or BPH)

Enlarged Prostate Quick Overview

A man's prostate gland usually starts to enlarge after he reaches 40 years of age. This condition is called benign prostatic hyperplasia (BPH). The condition has also been referred to as benign prostatic hypertrophy.

The prostate gland secretes a fluid that helps to nourish sperm. The gland itself surrounds the urethra, which is the tube that carries urine from the bladder out through the tip of the penis. As the prostate grows larger, it may press on the urethra. This narrowing of the urethra can cause some men with prostate enlargement to have trouble with urination. Prostate enlargement may be the most common health problem in men older than 60 years of age.

Enlarged Prostate Causes

The prostate gland, which is normally about the size and shape of a walnut, wraps around the urethra between the pubic bone and the rectum, below the bladder. In the early stage of prostate enlargement, the bladder muscle becomes thicker and forces urine through the narrowed urethra by contracting more powerfully. As a result, the bladder muscle may become more sensitive, causing a need to urinate more often and more suddenly.

The prostate grows larger due to an increase in the number of cells (hyperplasia). However, the precise reason for this increase is unknown. A variety of factors may be involved, including androgens (male hormones), estrogens, growth factors and other cell signaling pathways.

As the prostate grows larger and the urethra is squeezed more tightly, the bladder might not be able to fully compensate for the problem and completely empty. In some cases, blockage from prostate enlargement may cause repeated urinary tract infections and gradually result in bladder or kidney damage. It may also cause a sudden inability to urinate (acute urinary retention) -- a medical emergency.

Medically Reviewed by a Doctor on 2/5/2016
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Enlarged Prostate Surgeries

There are many surgeries to treat benign prostatic hyperplasia (BPH). But most have not been studied very much. The gold-standard surgery for BPH is transurethral resection of the prostate (TURP). When these new surgeries are studied, they are compared to TURP.

Other surgeries for BPH include:

  • Transurethral holmium laser ablation (HoLAP), in which a laser is used to destroy a portion of the prostate.
  • Transurethral holmium laser enucleation (HoLEP), in which a laser is used to completely remove the prostate.
  • Holmium laser resection of the prostate (HoLRP), in which a laser is used to remove a portion of the prostate.
SOURCE: Healthwise

Read What Your Physician is Reading on Medscape

Prostate Hyperplasia, Benign »

Benign prostatic hyperplasia (BPH) is a noncancerous enlargement of the prostate gland that may restrict the flow of urine from the bladder.

Read More on Medscape Reference »


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