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Medications and Drugs

Brand Names: Byetta Prefilled Pen

Generic Name: exenatide (Byetta) (Pronunciation: ex EN a tide)

What is Byetta (Byetta Prefilled Pen)?

Exenatide is an injectable diabetes medicine that helps control blood sugar levels. This medication helps your pancreas produce insulin more efficiently. Byetta is a short-acting form of exenatide.

Exenatide is used to treat type 2 diabetes. Other diabetes medicines are sometimes used in combination with exenatide if needed.

This medication guide provides information about the Byetta brand of exenatide. Bydureon is another brand of exenatide that is not covered in this medication guide.

Exenatide may also be used for purposes not listed in this medication guide.

What are the possible side effects of Byetta (Byetta Prefilled Pen)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using exenatide and call your doctor at once if you have a serious side effect such as:

  • swelling, weight gain, feeling short of breath, urinating less than usual or not at all;
  • drowsiness, confusion, mood changes, increased thirst, diarrhea;
  • dull pain in your middle or lower back;
  • severe pain in your upper stomach spreading to your back, vomiting; or
  • low blood sugar (headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery).

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about Byetta (Byetta Prefilled Pen)?

This medication guide provides information about the Byetta brand of exenatide. Bydureon is another brand of exenatide that is not covered in this medication guide.

Do not use exenatide to treat type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin). You should not use exenatide if you have severe kidney disease (or if you are on dialysis), of if you have a severe stomach disorder that causes slow digestion.

You should not use Byetta together with a fast-acting or short-acting insulin, such as insulin aspart (NovoLOG), insulin glulisine (Apidra), insulin lispro (HumaLOG), or regular insulin (HumuLIN R, NovoLIN R, and others). Do not use Byetta together with Bydureon.

You must use Byetta within 60 minutes (1 hour) BEFORE eating a meal. Do not use this medication after eating a meal.

Stop using exenatide and call your doctor at once if you have severe pain in your upper stomach spreading to your back, with nausea, vomiting, and a fast heart rate. These could be symptoms of pancreatitis.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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