Font Size
A
A
A
1

Familial Lipid Disorders


Topic Overview

A familial lipid disorder is a condition that runs in families. It causes very high levels of cholesterol. This condition can cause a person to get coronary artery disease (CAD) while still young. Because familial lipid disorders are rare, your doctor may only suspect one if you have:

Your family doctor may not have much experience with familial lipid disorders, so you may have to see a specialist, such as an endocrinologist. And some cardiologists specialize in lipid disorders as well as heart problems.

Types of familial lipid disorders

Disorder

Cholesterol level

Other details

Familial combined hyperlipidemia (FCHL)
  • High total cholesterol, usually with high triglycerides
  • High triglycerides and low HDL
Familial defective apolipoprotein B-100
Familial dysbetalipoproteinemia (type 3 hyperlipoproteinemia)
  • Total cholesterol of 300–600
  • Triglyceride of 400–800
  • CAD, heart attack, and stroke at a young age
  • Xanthomas, a skin condition in which small bumps of fat appear under the skin
Familial hypertriglyceridemia
  • Very high triglycerides
  • Risk for even higher triglycerides from other causes
Heterozygous familial hypercholesterolemia
  • Total cholesterol of 325–450
  • CAD before age 50
  • Small, pale ring around the iris of the eye
  • Xanthomas on tendons in young adults
Homozygous familial hypercholesterolemia
  • Total cholesterol of 500–1,000
  • CAD before age 20
  • Xanthomas on tendons within the first few months of life
1

eMedicineHealth Medical Reference from Healthwise

This information does not replace the advice of a doctor. Healthwise disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

To learn more visit Healthwise.org

© 1995-2012 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.





Medical Dictionary