Fever in Adults (cont.)
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A doctor will ask many questions in an effort to find the source of the fever:
A very thorough physical examination will be done in an effort to find the source of the fever. After the history is taken and physical examination is performed, the physician may know the cause of the fever. If the physician is not sure at this point, he or she may order certain tests to help make the diagnosis. Examples of diagnostic tests that may be ordered are
Based on the results of these tests, the physician usually will be able to find the cause of the fever. More specific tests, including imaging tests, may be done if needed if the initial tests do not suggest a cause for the fevers.
FUOs (fevers of unknown origin) are challenging, and often specialists need to be involved to help determine what further diagnostic testing may be needed (for example, endoscopy, PET scanning, echocardiography, or radionucleotide studies).
Medically Reviewed by a Doctor on 8/10/2015
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Fever of unknown origin (FUO) was defined in 1961 by Petersdorf and Beeson as the following: (1) a temperature greater than 38.3°C (101°F) on several occasions, (2) more than 3 weeks' duration of illness, and (3) failure to reach a diagnosis despite one week of inpatient investigation.