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February 10, 2012
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Fifth Disease (cont.)

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Fifth Disease Symptoms and Signs

  • Fifth disease usually starts with a mild vague illness and nonspecific symptoms. Fever occurs 15%-30% of the time, along with nasal congestion and drainage, sore throat, fatigue, muscle aches, and a headache. This lasts for several days.


  • Then, seven to 10 days later, the characteristic facial rash (the "slapped cheeks" appearance) develops abruptly. Typically, the facial rash is bright red. The child looks as if a hand has been slapped across his or her face. This rash fades in around four days.


  • A light pink rash begins on the arms and spreads to the trunk, buttocks, and thighs. This gradually fades to a lace-like pattern, then clears.
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Read What Your Physician is Reading on Medscape

Pediatrics, Fifth Disease or Erythema Infectiosum »

Erythema infectiosum is usually a benign childhood condition characterized by a classic slapped-cheek and lacy exanthem.

Read More on Medscape Reference »

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