Medications and Drugs
Brand Names: Fludara
Generic Name: fludarabine (injection) (Pronunciation: floo DAR a been)
What is fludarabine (Fludara)?
Fludarabine is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Fludarabine is used to treat B-cell chronic lymphocytic leukemia (CLL).
Fludarabine is usually given after other cancer medications have been tried without successful response to treatment.
Fludarabine may also be used for purposes not listed in this medication guide.
What are the possible side effects of fludarabine (Fludara)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about fludarabine (Fludara)?
Do not use fludarabine if you are pregnant. It could harm the unborn baby.
Before you receive fludarabine, tell your doctor if you have kidney disease, bone marrow problems or a weak immune system, any active infection, a history of skin cancer, or a history of a viral infection such as herpes zoster (shingles), Epstein-Barr, or a virus affecting the central nervous system.
If you need to have a blood transfusion, tell your caregivers ahead of time that you are being treated with fludarabine.
Fludarabine can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Visit your doctor regularly.
Do not receive a "live" vaccine while using fludarabine, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you.
Contact your doctor at once if you develop signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, mouth sores, or unusual weakness.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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