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Gallstones Overview

Gallstones (commonly misspelled gall stones or gall stone) are solid particles that form from bile in the gallbladder.

  • The gallbladder is a small saclike organ in the upper right part of the abdomen. It is located under the liver, just below the front rib cage on the right side.
  • The gallbladder is part of the biliary system, which includes the liver and the pancreas.
  • The biliary system, among other functions, produces bile and digestive enzymes.

Bile is a fluid made by the liver to help in the digestion of fats.

  • It contains several different substances, including cholesterol and bilirubin, a waste product of normal breakdown of blood cells in the liver.
  • Bile is stored in the gallbladder until needed.
  • When we eat a high-fat, high-cholesterol meal, the gallbladder contracts and injects bile into the small intestine via a small tube called the common bile duct. The bile then assists in the digestive process.
Picture of Gallstones
Picture of Gallstones

There are two types of gallstones: 1) cholesterol stones and 2) pigment stones.

  1. Patients with cholesterol stones are more common in the United States; cholesterol stones make up a majority of all gallstones. They form when there is too much cholesterol in the bile.
  2. Pigment stones form when there is excess bilirubin in the bile.

Gallstones can be any size, from tiny as a grain of sand to large as a golf ball.

  • Although it is common to have many smaller stones, a single larger stone or any combination of sizes is possible.
  • If stones are very small, they may form a sludge or slurry.
  • Whether gallstones cause symptoms depends partly on their size and their number, although no combination of number and size can predict whether symptoms will occur or the severity of the symptoms.

Gallstones within the gallbladder often cause no problems. If there are many or they are large, they may cause pain when the gallbladder responds to a fatty meal. They also may cause problems if they move out of the gallbladder.

  • If their movement leads to blockage of any of the ducts connecting the gallbladder, liver, or pancreas with the intestine, serious complications may result.
  • Blockage of a duct can cause bile or digestive enzymes to be trapped in the duct.
  • This can cause inflammation and ultimately severe pain, infection, and organ damage.
  • If these conditions go untreated, they can even cause death.

Up to 20% of adults in the United States may have gallstones, yet only 1% to 3% develop symptoms.

  • Hispanics, Native Americans, and Caucasians of Northern European descent are most likely to be at risk for gallstones. African Americans are at lower risk.
  • Gallstones are most common among overweight, middle-aged women, but the elderly and men are more likely to experience more serious complications from gallstones.
  • Women who have been pregnant are more likely to develop gallstones. The same is true for women taking birth control pills or on hormone/estrogen therapy as this can mimic pregnancy in terms of hormone levels.
Medically Reviewed by a Doctor on 7/28/2015

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Gallbladder Diet

Experts discuss foods that are good for your gallbladder, as well as what not to eat when you have gallbladder problems.

By Stephanie Watson
WebMD Feature
Reviewed by Venkat Mohan, MD

Most people never give a thought to the health of their gallbladder. The pear-shaped organ does have an important job, collecting and storing bile -- the fluid that helps the body digest fats. But unlike the heart, liver, and kidneys, the gallbladder isn't necessary to keep the body healthy and functioning. Even when it isn't working as well as it should and gallstones develop, most people are unaware that there is a problem.

Yet in a small percentage of people, gallstones can trigger a variety of symptoms, such as abdominal pain, bloating, nausea, and vomiting. When gallstone symptoms are frequent, recurrent, and especially uncomfortable, the typical treatment is surgery to remove the gallbladder.

"The majority of people with gallstones never develop symptoms their whole lives," says John Martin, MD, associate professor of medicine and surgery, and director of endoscopy at the Northwestern University Feinberg School of Medicine. "Once you start to develop symptoms, you're going to need to have the gallbladder taken out."

Although diet doesn't directly cause gallbladder problems -- and it won't cure them -- watching what you eat and keeping a healthy weight might help you prevent gallstones from forming and avoid some discomfort if you do develop gallstones.

WebMD. Gallstone Diet.

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