Genital Warts (HPV Infection) Glossary of Terms

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5-fluorouracil: An anticancer drug, See: Fluorouracil.

Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer).

Acetic acid: The acid most commonly associated with vinegar. Acetic acid is a two-carbon carboxylic acid. Its formula is: CH3COOH. It is the most commercially important organic acid and is used in the manufacture of a broad range of chemical products, such as plastics and insecticides.

Airway: The path air follows to get into and out of the lungs. The mouth and nose are the normal entry and exit ports. Entering air then passes through the back of the throat (pharynx), continues through the voice box (larynx), down the trachea, and finally out the branching tubes known as bronchi.

Anesthesia: Loss of feeling or awareness. A general anesthetic puts the person to sleep. A local anesthetic causes loss of feeling in a part of the body such as a tooth or an area of skin without affecting consciousness. Regional anesthesia numbs a larger part of the body such as a leg or arm, also without affecting consciousness. The term "conduction anesthesia" encompasses both local and regional anesthetic techniques. Many surgical procedures can be done with conduction anesthesia without significant pain. In many situations, such as a C-section, conduction anesthesia is safer and therefore preferable to general anesthesia. However, there are also many types of surgery in which general anesthesia is clearly appropriate.

Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
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Bumps: The raised area of a bump or bruise results from blood leaking from these injured blood vessels into the tissues as well as from the body's response to the injury. A purplish, flat bruise that occurs when blood leaks out into the top layers of skin is referred to as an ecchymosis.

Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Cervical: Having to do with any kind of neck including the neck on which the head is perched and the neck of the uterus. The word "cervix" in Latin means "neck". That is why cervical vertebrae and cervical cancer involve quite disparate parts of the anatomy joined only by the meaning of the word "cervix".

Cervical cancer: Cancer of the entrance to the womb (uterus). The cervix is the lower, narrow part of the uterus (womb). The uterus, a hollow, pear-shaped organ, is located in a woman's lower abdomen, between the bladder and the rectum. The cervix forms a canal that opens into the vagina, which leads to the outside of the body.

Cervix: The cervix is the lower, narrow part of the uterus (womb). The uterus, a hollow, pear-shaped organ, is located in a woman's lower abdomen, between the bladder and the rectum. The cervix forms a canal that opens into the vagina, which leads to the outside of the body.

Colposcope: A lighted magnifying instrument used by a gynecologist to examine the tissues of the vagina and the cervix. The procedure is called colposcopy.

Colposcopy: A procedure in which a gynecologist uses a lighted magnifying instrument which is called a colposcope to examine the tissues of the vagina and the cervix.

Condyloma: A wartlike growth around the anus, vulva, or glans penis. There are three major types of condylomas, each of which is sexually transmitted. These include condyloma acuminatum or genital warts, condyloma latum (a form of secondary syphilis), and condyloma subcutaneum or molluscum contagiosum.
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Cryoprobe: A surgical probe, a long slender pointed surgical instrument, used to apply extreme cold to tissues. From cryo- from the Greek kryos meaning cold + probe.

Cryotherapy: Literally, "cold therapy." Cryotherapy, sometimes referred to as cryosurgery, is a procedure used to destroy tissue of both benign and malignant lesions by the freezing and re-thawing process. Liquid nitrogen is the most commonly used freezing source for cryotherapy. Examples of the uses of cryotherapy in medicine are the treatment (removal) of various types of skin lesions , the treatment of dysplastic (precancerous) tissue of the uterine cervix, and the treatment of some prostate cancers.
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Cure: 1. To heal, to make well, to restore to good health. Cures are easy to claim and, all too often, difficult to confirm.
2. A time without recurrence of a disease so that the risk of recurrence is small, as in the 5-year cure rate for malignant melanoma.
3. Particularly in the past, a course of treatment. For example, take a cure at a spa.
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Dermatologist: A doctor who specializes in the diagnosis and treatment of skin problems.

Diagnosis: 1 The nature of a disease; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies. 3 The identification of any problem. The diagnosis was a plugged IV.
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Discharge: 1.The flow of fluid from part of the body, such as from the nose or vagina.
2. The passing of an action potential, such as through a nerve or muscle fiber.
3. The release of a patient from a course of care. The doctor may then dictate a discharge summary.

Electrodesiccation: Use of an electric current to destroy cancerous tissue and control bleeding.

Excision: 1. Surgical removal, as in the excision of a tumor. 2. The removal as if by surgery, as in base excision repair.
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FDA: The Food and Drug Administration, an agency within the U.S. Public Health Service, which is a part of the Department of Health and Human Services.
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Foreskin: The fold of skin which covers the head (the glans) of the penis. Also called the prepuce.
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Genital: Pertaining to the external and internal organs of reproduction. (Not to be confused with genetic.)

Hair follicle: A sac from which a hair grows and into which the sebaceous (oil) glands open. The follicle is lined by cells derived from the epidermal (outside) layer of the skin.
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HPV: See: Human papillomavirus.

Human papillomavirus: HPV. A family of over 100 viruses including those which cause warts and are transmitted by contact. Some types of HPV are associated with tumors of the genital tract including, notably, cancer of the cervix.
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Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Interferon: A naturally occurring substance that interferes with the ability of viruses to reproduce. Interferon also boosts the immune system.
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Itching: An uncomfortable sensation in the skin that feels as if something is crawling on the skin or in the skin, and makes the person want to scratch the affected area.
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Labia: The lips, either the lips around the mouth (the oral labia) or the lip-like external female genitalia (the labia majora and labia minora). See also: Labial; Labrose.

Labia minora: The smaller (minor) inside pair of labia (lips) of the vulva (the female external genitalia).

Labial: Pertaining to the lip, one of the fleshy folds which surround the opening of the mouth or the vagina.
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Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."

Laser: A powerful beam of light that can produce intense heat when focused at close range. Lasers are used in medicine in microsurgery, cauterization, for diagnostic purposes, etc. For example, lasers are employed in microsurgery to cut tissue and remove tissue.
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Lesion: Pronounced "lee-sion" with the emphasis on the "lee," a lesion can be almost any abnormality involving any tissue or organ due to any disease or any injury.
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Liquid nitrogen: Nitrogen in a liquid state. Liquid nitrogen is supercool -- about 200 degrees Celsius (320 degrees Fahrenheit) below zero -- and is used for cryopreservation, cryosurgery, and cryomedicine.
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Microscopic: So small it cannot be seen without the aid of microscope. As opposed to macroscopic (large enough to be seen with naked eye). A tiny tumor is microscopic while a big tumor is macroscopic.

Nitrogen: Element number 7, a colorless, odorless, tasteless gas that is biologically important. Nitrogen is a constituent of protein and nucleic acids and is present in all living cells. Nitrogen does not support respiration and is fatal if breathed alone, because of the lack of oxygen. Nitrogen is soluble in the blood and body fluids and, when released as bubbles of gas, can have serious or even fatal consequences.
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Obstruction: Blockage of a passageway. See, for example: Airway obstruction; Intestinal obstruction.

Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia. Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Pap Smear: A screening test for cervical cancer based on the examination under the microscope of cells collected from the cervix, smeared on a slide and specially stained to reveal premalignant (before cancer) and malignant (cancer) changes as well as changes due to noncancerous conditions such as inflammation from infections.
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Papillomatosis: A disorder with numerous papillomas wart growths).
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Penile: Of or pertaining to the penis.

Penis: The external male sex organ used to copulate and ejaculate semen and to convey urine outside the body.
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Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
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Premalignant: Pertaining to tissue that is not yet malignant, but is poised to become malignant. Appropriate clinical and laboratory studies are designed to detect premalignant tissue while it is still in a premalignant stages. A large battery of techniques are generally available to remove or kill the tissue, thereby preventing the development of cancer. The proper treatment method depends on the particular premalignant tissue involved. Following are a few examples of premalignant growths:
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Recurrence: The return of a sign, symptom or disease after a remission. The reappearance of cancer cells at the same site or in another location is, unfortunately, a familiar form of recurrence.
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Recurrent: Back again. A recurrent fever is a fever that has returned after an intermission: a recrudescent fever.

Recurrent respiratory papillomatosis: Recurrent respiratory papillomatosis involves the growth of numerous warty growths in the larynx on the vocal cords in children and young adults.
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Respiratory: Having to do with respiration, the exchange of oxygen and carbon dioxide. From the Latin re- (again) + spirare (to breathe) = to breathe again.

Scrotum: A pouch of skin which contains the testes, epididymides, and lower portions of the spermatic cords.

Sexually transmitted disease: Any disease transmitted by sexual contact; caused by microorganisms that survive on the skin or mucus membranes of the genital area; or transmitted via semen, vaginal secretions, or blood during intercourse. Because the genital areas provide a moist, warm environment that is especially conducive to the proliferation of bacteria, viruses, and yeasts, a great many diseases can be transmitted this way. They include AIDS, chlamydia, genital herpes, genital warts, gonorrhea, syphilis, yeast infections, and some forms of hepatitis. Also known as a morbus venereus or venereal disease.
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STD: Sexually transmitted disease.

Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Therapy: The treatment of disease.
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Trauma: Any injury, whether physically or emotionally inflicted. "Trauma" has both a medical and a psychiatric definition. Medically, "trauma" refers to a serious or critical bodily injury, wound, or shock. This definition is often associated with trauma medicine practiced in emergency rooms and represents a popular view of the term. In psychiatry, "trauma" has assumed a different meaning and refers to an experience that is emotionally painful, distressful, or shocking, which often results in lasting mental and physical effects.
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Urethra: The transport tube leading from the bladder to discharge urine outside the body. In males, the urethra travels through the penis, and carries semen as well as urine. In females, the urethra is shorter than in the male and emerges above the vaginal opening, as indicated here:

Urinary: Having to do with the kidneys, ureters, and bladder. The urinary system represents the functional and anatomic aspects of the kidneys, ureters, and bladder.

Urine: Liquid waste. The urine is a clear, transparent fluid. It normally has an amber color. The average amount of urine excreted in 24 hours is from 40 to 60 ounces (about 1,200 cubic centimeters). Chemically, the urine is mainly an aqueous (watery) solution of salt (sodium chloride) and substances called urea and uric acid. Normally, it contains about 960 parts of water to 40 parts of solid matter. Abnormally, it may contain sugar (in diabetes), albumen (a protein) (as in some forms of kidney disease), bile pigments (as in jaundice), or abnormal quantities of one or another of its normal components.

Vagina: The muscular canal extending from the cervix to the outside of the body. It is usually six to seven inches in length, and its walls are lined with mucus membrane. It includes two vaultlike structures, the anterior (front) vaginal fornix and the posterior (rear) vaginal fornix. The cervix protrudes slightly into the vagina, and it is through a tiny hole in the cervix (the os) that sperm make their way toward the internal reproductive organs. The vagina also includes numerous tiny glands that make vaginal secretions.
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Vaginal discharge: Vaginal discharge is a fluid produced by glands in the vaginal wall and cervix that drains from the opening of the vagina. The amount and appearance of normal vaginal discharge varies throughout the menstrual cycle. An increase in the amount of vaginal discharge, an abnormal odor or consistency of the fluid, or pain that accompanies vaginal discharge can all be signs of infection or other disorders. Such disorders include (this is not an all inclusive list) bacterial vaginosis, yeast vaginitis, and vaginitis.

Vaginal opening: The opening to the muscular canal extending from the cervix to the outside of the body. The word "vagina" is a Latin word meaning "a sheath or scabbard", a scabbard into which one might slide and sheath a sword. The "sword" in the case of the anatomic vagina was the penis. Love and war, it would seem, have been connected in the minds of people for millennia.

Venereal: Having to do with sexual contact. The word venereal comes from Venus, the Roman goddess of love. A venereal disease (morbus venereus) is contracted and transmitted by sexual contact. Today the more common term is sexually transmitted, as in a sexually transmitted infection and sexually transmitted disease.

Viral: Of or pertaining to a virus. For example, "My daughter has a viral rash."

Virus: A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell. A virus invades living cells and uses their chemical machinery to keep itself alive and to replicate itself. It may reproduce with fidelity or with errors (mutations)-this ability to mutate is responsible for the ability of some viruses to change slightly in each infected person, making treatment more difficult.
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Wart: A local growth of the outer layer of the skin (the epidermis) caused by a virus. The virus of warts (a papillomavirus) is transmitted by contact. The contact can be with a wart on someone else or one on oneself (autoinoculation).
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