Glaucoma Overview Glossary of Medical Terms

Abdominal: Relating to the abdomen, the belly , that part of the body that contains all of the structures between the chest and the pelvis . The abdomen is separated anatomically from the chest by the diaphragm , the powerful muscle spanning the body cavity below the lungs .
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Abdominal pain: Pain in the belly (the abdomen). Abdominal pain can come from conditions affecting a variety of organs. The abdomen is an anatomical area that is bounded by the lower margin of the ribs above, the pelvic bone (pubic ramus) below, and the flanks on each side. Although abdominal pain can arise from the tissues of the abdominal wall that surround the abdominal cavity (the skin and abdominal wall muscles), the term abdominal pain generally is used to describe pain originating from organs within the abdominal cavity (from beneath the skin and muscles). These organs include the stomach, small intestine, colon, liver, gallbladder, and pancreas.
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Acute: Of abrupt onset, in reference to a disease. Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care.
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Acute angle-closure glaucoma: Increased pressure in the front chamber (anterior chamber) of the eye due to sudden (acute) blockage of the normal circulation of fluid within the eye. The block takes place at the angle of the anterior chamber formed by its junction of the cornea with the iris. This angle can be seen by simply looking at someone's eye from the side. Angle-closure glaucoma tends to affect people born with a narrow angle. People of Asian and Eskimo ancestry are at higher risk of developing it. Age and family history are risk factors. It occurs in older women more often than others.
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Anatomy: The study of form. Gross anatomy involves structures that can be seen with the naked eye. It is as opposed to microscopic anatomy (or histology) which involves structures seen under the microscope. Traditionally, both gross and microscopic anatomy have been studied in the first year of medical school in the U.S. The most celebrated textbook of anatomy in the English-speaking world is Gray's Anatomy, still a useful reference book. The word "anatomy" comes from the Greek ana- meaning up or through + tome meaning a cutting. Anatomy was once a "cutting up" because the structure of the body was originally learned through dissecting it, cutting it up. The abbreviation for anatomy is anat.
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Angle-closure glaucoma: This condition can be acute or chronic. It consists of increased pressure in the front chamber (anterior chamber) of the eye due to sudden (acute) or slowly progressive (chronic) blockage of the normal circulation of fluid within the eye. The block takes place at the angle of the anterior chamber formed by its junction of the cornea with the iris. This angle can be seen by simply looking at someone's eye from the side. Angle-closure glaucoma tends to affect people born with a narrow angle. People of Asian and Eskimo ancestry are at higher risk of developing it. Age and family history are risk factors. It occurs in older women more often than others. When the pupil of the eye is wide open (dilated), the iris is retracted and thickened and it block the canal of Schlemm, a key component of the drainage pathway for fluid within the eye. Blocking the drainage canal of Schlemm sends the pressure within the eye up. With acute angle-closure glaucoma, there is an abrupt increase in intraocular pressure (IOP) due to the buildup of aqueous (fluid) in the eye. The high pressure can damage the optic nerve (the nerve to the eye) and lead to blindness. The elevated pressure is best detected before the appearance of symptoms. That is why when the eyes are dilated in a doctor's office for a refraction, eye pressures are checked. When symptoms of acute angle glaucoma do develop, they include severe eye and facial pain, nausea and vomiting, decreased vision, blurred vision and seeing haloes around light. The eye in a far advanced case of angle closure glaucoma appears red with a steamy (clouded) cornea and a fixed (nonreactive) dilated pupil. Acute angle-closure glaucoma is an emergency because optic nerve damage and vision loss can occur within hours of the onset of the problem. Administering medications to lower the pressure within the eye is done first. In the past, a piece of the iris was then surgically removed in a procedure called an iridectomy to make a hole in the iris and create a channel (other than the canal of Sclemm) to permit the free flow of fluid. Today, a comparable procedure can be done by laser to burn a small hole in the iris to keep the intraocular pressure within normal limits. This condition can be chronic (progressing slowly or occurring persistently) or acute (occurring suddenly). Chronic angle-closure glaucoma, like the more common type of glaucoma (open-angle glaucoma), may cause vision damage without symptoms.
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Aqueous humor: In medicine, humor refers to a fluid (or semifluid) substance. Thus, the aqueous humor is the fluid normally present in the front and rear chambers of the eye. It is a clear, watery fluid that flows between and nourishes the lens and the cornea; it is secreted by the ciliary processes.
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Blind: 1. Unable to see. Without part or all of the sense of sight.
2. In a clinical trial, not to know the treatment given or received. The participant is not told whether they are in the experimental or control arm of the study. Also called masked.
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Blindness: Loss of useful sight. Blindness can be temporary or permanent. Damage to any portion of the eye, the optic nerve, or the area of the brain responsible for vision can lead to blindness. There are numerous (actually, innumerable) causes of blindness. The current politically correct terms for blindness include visually handicapped and visually challenged.
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Blurred vision: Lack of sharpness of vision with, as a result, the inability to see fine detail. Blurred vision can occur when a person who wears corrective lens is without them. Blurred vision can also be an important clue to eye disease.
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Breathing: The process of respiration, during which air is inhaled into the lungs through the mouth or nose due to muscle contraction, and then exhaled due to muscle relaxation.
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Childhood: (1) The time for a boy or girl from birth until he or she is an adult. (2) The more circumscribed period of time from infancy to the onset of puberty .
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Chin: Medically, the mentum. The lower portion of the face below the lower lip including the prominence of the lower jaw and the line of fusion of the two separate halves of the jawbone ( mandible ). This line of fusion (called the symphysis menti) encloses a triangular area at tip of the chin (termed the mental protuberance). On each side, below the second premolar tooth, is the mental foramen , an opening for the passage of blood vessels and a nerve that supply the chin.
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Condition: The term "condition" has a number of biomedical meanings including the following:

1. An unhealthy state, such as in "this is a progressive condition."
2. A state of fitness, such as "getting into condition."
3. Something that is essential to the occurrence of something else; essentially a "precondition."
4. As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.

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Congenital: Present at birth. A condition that is congenital is one that is present at birth. There are numerous uses of "congenital" in medicine. There are, for example, congenital abnormalities. (For more examples, see below.)
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Cornea: The clear front window of the eye that transmits and focuses light into the eye.
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Cupping: 1. A cup-shaped depression, as in the head of the optic nerve in the eye.
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Depression : An illness that involves the body, mood, and thoughts, that affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. A depressive disorder is not the same as a passing blue mood. It is not a sign of personal weakness or a condition that can be wished away. People with a depressive disease cannot merely "pull themselves together" and get better. Without treatment, symptoms can last for weeks, months, or years. Appropriate treatment, however, can help most people with depression.
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Dilate: To stretch or enlarge. It comes from the Latin verb "dilatare" meaning "to enlarge or expand."
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Dilation: The process of enlargement, stretching, or expansion. The word "dilatation" means the same thing. Both come from the Latin "dilatare" meaning "to enlarge or expand."
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Family history: The family structure and relationships within the family, including information about diseases in family members.
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Glaucoma : A common eye condition in which the fluid pressure inside the eyes rises because of slowed fluid drainage from the eye. If untreated, it may damage the optic nerve and other parts of the eye, causing the loss of vision or even blindness.
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Headache : A pain in the head with the pain being above the eyes or the ears, behind the head (occipital), or in the back of the upper neck. Headache, like chest pain or back ache, has many causes.
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Hospital: It may seem unnecessary to define a "hospital" since everyone knows the nature of a hospital. A hospital began as a charitable institution for the needy, aged, infirm, or young.
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Humor: In medicine, humor refers to a fluid (or semifluid) substance. Thus, the aqueous humor is the fluid normally present in the front and rear chambers of the eye. The humors ran through an ancient theory that held that health came from balance between the bodily liquids. These liquids were termed humors. Disease arose when there was imbalance between these humors.
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Hypertension: High blood pressure , defined as a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
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Incision: A cut. When making an incision, a surgeon is making a cut.
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Injury: Harm or hurt. The term "injury" may be applied in medicine to damage inflicted upon oneself as in a hamstring injury or by an external agent on as in a cold injury . The injury may be accidental or deliberate, as with a needlestick injury . The term "injury" may be synonymous (depending on the context) with a wound or with trauma .
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Intraocular: In the eye. The intraocular pressure is the pressure within the eye.
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Intraocular pressure: The pressure created by the continual renewal of fluids within the eye. The intraocular pressure is increased in glaucoma .
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Iris: The iris is the circular, colored curtain of the eye. Its opening forms the pupil. The iris helps regulate the amount of light that enters the eye.
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Laser: A powerful beam of light that can produce intense heat when focused at close range. Lasers are used in medicine in microsurgery, cauterization, for diagnostic purposes, etc. For example, lasers are employed in microsurgery to cut tissue and remove tissue.
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Laser surgery: A type of surgery that uses the cutting power of a laser beam to make bloodless cuts in tissue or remove a surface lesion such as a skin tumor. There are a number of different types of lasers that differ in emitted light wavelengths and power ranges and in their ability to clot, cut, or vaporize tissue. Among the commonly used lasers are the pulsed-dye laser, the YAG laser , the CO2 (carbon dioxide) laser, the argon laser, the excimer laser , the KTP laser, and the diode laser.
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Medication: 1. A drug or medicine. 2. The administration of a drug or medicine. (Note that "medication" does not have the dangerous double meaning of "drug.")
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Nausea: Nausea, is the urge to vomit. It can be brought by many causes including, systemic illnesses, such as influenza , medications, pain, and inner ear disease. When nausea and/or vomiting are persistent, or when they are accompanied by other severe symptoms such as abdominal pain , jaundice , fever, or bleeding, a physician should be consulted.
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Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system .
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Normal range: By convention, the normal range for whatever (a particular test, condition, symptom, behavior, etc.) is set to cover ninety-five percent (95%) of all values from the general population. Five percent (5%) of results consequently fall outside the normal range. Values that prove normal can therefore sometimes be outside the normal range.
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Normal tension glaucoma: See: Glaucoma, normal tension .
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Nutrition : 1) The science or practice of taking in and utilizing foods. 2) A nourishing substance, such as nutritional solutions delivered to hospitalized patients via an IV or IG tube.
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Ocular: Having to do with the eye.
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Onset: In medicine, the first appearance of the signs or symptoms of an illness as, for example, the onset of rheumatoid arthritis . There is always an onset to a disease but never to the return to good health. The default setting is good health.
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Open-angle glaucoma : Glaucoma in which the aqueous (fluid) that flows through the pupil into the anterior (front) chamber of the eye cannot get through a filtration system called the trabecular meshwork into the drainage canals, causing pressure to build up within the eye which can damage the optic nerve and impair vision.
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Operation: Although there are many meanings to the word "operation", in medicine it refers to a surgical procedure.
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Ophthalmologist: An eye doctor. A physician practicing ophthalmology. An ophthalmologist is an M.D.
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Ophthalmology: The art and science of eye medicine.
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Optic: Having to do with vision.
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Optic nerve: The optic nerve connects the eye to the brain. The optic nerve carries the impulses formed by the retina, the nerve layer that lines the back of the eye and senses light and creates impulses. These impulses are dispatched through the optic nerve to the brain, which interprets them as images. Using an ophthalmoscope, the head of the optic nerve can be easily seen. It can be viewed as the only visible part of the brain (or extension of it).
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Oxygen: A colorless, odorless and tasteless gas that makes up about 20% of the air we breathe (and at least half the weight of the entire solid crust of the earth) and which combines with most of the other elements to form oxides. Oxygen is essential to human, animal and plant life.
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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Peripheral: Situated away from the center, as opposed to centrally located.
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Peripheral vision: Side vision. The ability to see objects and movement outside of the direct line of vision. Peripheral vision is the work of the rods, nerve cells located largely outside the macula (the center) of the retina. The rods are also responsible for night vision and low-light vision but are insensitive to color. As opposed to central vision.
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Pharmacy: A location where prescription drugs are sold. A pharmacy is, by law, constantly supervised by a licensed pharmacist.
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Primary: First or foremost in time or development. The primary teeth (the baby teeth) are those that come first. Primary may also refer to symptoms or a disease to which others are secondary.
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Prostaglandin: One of a number of hormone-like substances that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation. Prostaglandins are derived from a chemical called arachidonic acid.
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Pulse: The rhythmic contraction and expansion of an artery due to the surge of blood from the beat of the heart. The pulse is most often measured by feeling the arteries of the wrist. There is also a pulse, although far weaker, in veins.
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Pupil: The opening of the iris. The pupil may appear to open (dilate) and close (constrict) but it is really the iris that is the prime mover; the pupil is merely the absence of iris. The pupil determines how much light is let into the eye. Both pupils are usually of equal size. If they are not, that is termed anisocoria (from "a-", not + "iso", equal + "kore", pupil = not equal pupils).
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Rest: 1. Repose. Relaxation.
2. A fragment of embryonic tissue that has been retained after the period of embryonic development. Also called an embryonic rest.
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Risk factor: Something that increases a person's chances of developing a disease.
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Sensitivity: 1. In psychology, the quality of being sensitive. As, for example, sensitivity training, training in small groups to develop a sensitive awareness and understanding of oneself and of ones relationships with others. 2. In disease epidemiology, the ability of a system to detect epidemics and other changes in disease occurrence. 3. In screening for a disease, the proportion of persons with the disease who are correctly identified by a screening test. 4. In the definition of a disease, the proportion of persons with the disease who are correctly identified by defined criteria.
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Stage: As regards cancer , the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging .
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Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Tension: 1) The pressure within a vessel , such as blood pressure : the pressure within the blood vessels. For example, elevated blood pressure is referred to as hypertension . 2) Stress, especially stress that is translated into clenched scalp muscles and bottled-up emotions or anxiety. This is the type of tension blamed for tension headaches.
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Therapy: The treatment of disease .
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Tonometry: A standard eye test that determines the fluid pressure inside the eye. Increased pressure is a possible sign of glaucoma , a common and potentially very serious eye problem if not detected and treated promptly. It is recommended that adults over age 40 have tonometry for glaucoma every 3 to 5 years by having their eye pressures measured.
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Visual field: The entire area that can be seen when the eye is directed forward, including that which is seen with peripheral vision.
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