Glutamine

Are there any interactions with medications?

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Lactulose
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Lactulose helps decrease ammonia in the body. Glutamine is changed into ammonia in the body. Taking glutamine along with lactulose might decrease the effectiveness of lactulose.

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Medications for cancer (Chemotherapy)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

There is some concern that glutamine might decrease the effectiveness of some medications for cancer (chemotherapy). But it is too soon to know if this interaction occurs.

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Medications used to prevent seizures (Anticonvulsants)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Medications used to prevent seizures affect chemicals in the brain. Glutamine may also affect chemicals in the brain. By affecting chemicals in the brain, glutamine may decrease the effectiveness of medications used to prevent seizures.

Some medications used to prevent seizures include phenobarbital, primidone (Mysoline), valproic acid (Depakene), gabapentin (Neurontin), carbamazepine (Tegretol), phenytoin (Dilantin), and others.

Dosing considerations for Glutamine.

The following doses have been studied in scientific research:

BY MOUTH

• For reducing mouth soreness due to chemotherapy: glutamine suspension 4 grams, swish and swallow every four hours around the clock starting with the first dose of chemotherapy and continued until hospital discharge or resolution of symptoms.
• For HIV wasting: 8-40 grams per day has been used. However, 40 grams daily may work best.