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Goldenseal

How does Goldenseal work?

Goldenseal contains the chemical berberine, which might have effects against bacteria and fungi. For example, it can prevent the bacteria Escherichia coli (E. coli) from binding to urinary tract walls. Berberine also has properties that can lower blood pressure and improve irregular heartbeats. In addition, early research suggests that berberine can lower blood sugar and "bad" low-density lipoprotein (LDL) cholesterol.

Many of the important chemicals in goldenseal are poorly absorbed when taken by mouth and might not reach the concentrations needed to have significant effects in humans. So, it is unknown whether goldenseal has the same benefits as berberine.

Are there safety concerns?

Goldenseal is POSSIBLY SAFE for most adults when taken by mouth as a single dose. There is not enough reliable information to know if goldenseal is safe for long-term use.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Using goldenseal during pregnancy or breast-feeding is LIKELY UNSAFE for the infant. A hazardous chemical in goldenseal can cross the placenta and can also find its way into breast milk. Brain damage (kernicterus) has developed in newborn infants exposed to goldenseal. Do not use goldenseal during pregnancy or breast-feeding.

Children: Don't use goldenseal in newborn babies. It is LIKELY UNSAFE for them. It might cause brain damage (kernicterus).

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.



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