Gotu Kola

Are there any interactions with medications?

---

Sedative medications (CNS depressants)
Interaction Rating: Major Do not take this combination.

Large amounts of gotu kola might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking gotu kola along with sedative medications might cause too much sleepiness.

Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.

---

Medications that can harm the liver (Hepatotoxic drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Gotu kola might harm the liver. Taking gotu kola along with medication that might also harm the liver can increase the risk of liver damage.

Some medications that can harm the liver include acetaminophen (Tylenol and others), amiodarone (Cordarone), carbamazepine (Tegretol), isoniazid (INH), methotrexate (Rheumatrex), methyldopa (Aldomet), fluconazole (Diflucan), itraconazole (Sporanox), erythromycin (Erythrocin, Ilosone, others), phenytoin (Dilantin), lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor), and many others.

Dosing considerations for Gotu Kola.

The following doses have been studied in scientific research:

BY MOUTH:

• For blood circulation problems in the legs (venous insufficiency): 60-180 mg daily of gotu kola extract.