The prognosis is determined by the patient’s response to growth hormone replacement therapy and the underlying cause of the deficiency.

• Muscle mass may increase.
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• The patient may lose weight.
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• Exercise tolerance and performance may be increased.
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• Energy may increase.
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• Mood may improve.

Complications of growth hormone deficiency may include the following:

• Premature cardiovascular disease
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• Osteoporosis (a condition involving decreased bone mass and density)
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• Mental and emotional problems
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• Insulin resistance
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• Obesity and its complications
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