Medications

Doctors may use antibiotics when the guttate psoriasis is related to a streptococcal infection. They may choose an antibiotic that will act on a wide range of bacteria. Always tell your doctor what drugs you are currently taking because of the possibility of drug reactions.

Erythromycin (EES, E-Mycin, Ery-Tab) - Reduces inflammation and is used to treat bacterial infections. The usual dosing is one tablet per day by mouth for about 7-14 days. People with allergies to erythromycin or who have liver problems should not take this drug. Discontinue use if nausea, vomiting, fatigue, intestinal cramping, or fever occurs.

Penicillin VK (Veetids, Beepen-VK) - Is used to treat bacterial infections. The usual dosing is one tablet per day by mouth for about 10-14 days. People with allergies to penicillin should not take this drug. Caution is taken with the dosing of this drug in those who have reduced kidney function.

Rifampin (Rifadin, Rimactane) - Recommended for resistant cases of streptococcal infection. If the doctor thinks it is possible that the infection will last a long time and you may become a chronic carrier of the bacteria, he or she may prescribe this drug. Rifampin is usually given in addition to either erythromycin or penicillin. The drug is taken by mouth over the course of 5 days.

You should be aware of possible allergic reactions to any antibiotic used, especially penicillin. Stop taking the drug if an allergic reaction is suspected. Patients who are sensitive to penicillin generally do well on erythromycin. Cephalosporin is an antibiotic that can also be used for streptococcal infections, but some cross-sensitivity with penicillins has been documented.