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The breast enlargement of gynecomastia is usually symmetrical in location with regard to the nipple and has a rubbery or firm feel. Both sides are typically affected, although it can develop on only one side. The enlargement may be greater on one side even if both sides are involved. Gynecomastia is not accompanied by severe pain, although the enlarged area may be sensitive or tender.
In contrast to gynecomastia, male breast cancer is usually located only on one side and is not necessarily centered around the nipple. Other symptoms suggestive of cancer include a hard or firm feeling to the tissue, dimpling of the skin, retraction of the nipple, nipple discharge, and enlargement of the underarm (axillary) lymph nodes.
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