Heart and Lung Transplant Glossary of Medical Terms

Acetone: In the body, a chemical that is formed when the body uses fat instead of glucose (sugar) for energy. The formation of acetone means that cells lack insulin or cannot effectively use available insulin to burn glucose for energy. Acetone passes through the body into the urine as one of the so-called ketone bodies.
See the entire definition of Acetone

Acne: Localized skin inflammation as a result of overactivity of the oil glands at the base of hair follicles. Acne happens when oil (sebaceous) glands come to life around puberty, when these glands are stimulated by male hormones that are produced in the adrenal glands of both boys and girls.
See the entire definition of Acne

Acute: Of abrupt onset, in reference to a disease. Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care.
See the entire definition of Acute

Antiviral: An agent that kills a virus or that suppresses its ability to replicate and, hence, inhibits its capability to multiply and reproduce.
See the entire definition of Antiviral

Aorta: The largest artery in the body, the aorta arises from the left ventricle of the heart, goes up (ascends) a little ways, bends over (arches), then goes down (descends) through the chest and through the abdomen to where ends by dividing into two arteries called the common iliac arteries that go to the legs.
See the entire definition of Aorta

Arms: An appendage in anatomy and in clinical trials . See: Arm .
See the entire definition of Arms

Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
See the entire definition of Bacteria

Bacterial: Of or pertaining to bacteria . For example, a bacterial lung infection .
See the entire definition of Bacterial

Bilateral: Having, or relating to, two sides. Bilateral is as opposed, for example, to unilateral (which means having, or relating to, one side).
See the entire definition of Bilateral

Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
See the entire definition of Biopsy

Blood: The familiar red fluid in the body that contains white and red blood cells , platelets , proteins , and other elements. The blood is transported throughout the body by the circulatory system . Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.
See the entire definition of Blood

Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle . It's measurement is recorded by two numbers. The first ( systolic pressure) is measured after the heart contracts and is highest. The second ( diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called " hypertension ".
See the entire definition of Blood pressure

Blood sugar: Blood glucose . See also: High blood sugar ; Low blood sugar .
See the entire definition of Blood sugar

Bone: Bone is the substance that forms the skeleton of the body. It is composed chiefly of calcium phosphate and calcium carbonate . It also serves as a storage area for calcium, playing a large role in calcium balance in the blood.
See the entire definition of Bone

Bone marrow: The soft blood-forming tissue that fills the cavities of bones and contains fat and immature and mature blood cells, including white blood cells, red blood cells, and platelets. Diseases or drugs that affect the bone marrow can affect the total counts of these cells.
See the entire definition of Bone marrow

Bowel: Another name for the intestine . The small bowel and the large bowel are the small intestine and large intestine , respectively.
See the entire definition of Bowel

Bridge: A set of one or more false teeth supported by a metal framework, used to replace one or more missing teeth.
See the entire definition of Bridge

Bronchiolitis: Inflammation of the bronchioles, the airways that extend beyond the bronchi and terminate in the alveoli. Bronchiolitis is due to viral infections such as parainfluenza, influenza , adenovirus and, especially, respiratory syncytial virus (RSV).
See the entire definition of Bronchiolitis

Bronchoscopy : A procedure that permits the doctor to see the breathing passages through a lighted tube.
See the entire definition of Bronchoscopy

Cardiac: Having to do with the heart.
See the entire definition of Cardiac

Cardiovascular: The circulatory system comprising the heart and blood vessels which carries nutrients and oxygen to the tissues of the body and removes carbon dioxide and other wastes from them.
See the entire definition of Cardiovascular

Cardiovascular disease: Disease affecting the heart or blood vessels.
See the entire definition of Cardiovascular disease

Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane .
See the entire definition of Cell

Chest: The area of the body located between the neck and the abdomen . The chest contains the lungs , the heart and part of the aorta . The walls of the chest are supported by the dorsal vertebrae , the ribs , and the sternum .
See the entire definition of Chest

Chest pain: There are many causes of chest pain. One is angina which results from inadequate oxygen supply to the heart muscle. Angina can be caused by coronary artery disease or spasm of the coronary arteries. Chest pain can also be due to a heart attack (coronary occlusion) and other important diseases such as, for example, dissection of the aorta and a pulmonary embolism . Do not try to ignore chest pain and "work (or play) though it." Chest pain is a warning to seek medical attention.
See the entire definition of Chest pain

Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
See the entire definition of Chronic

Chronic obstructive pulmonary disease : COPD. Any disorder that persistently obstructs bronchial airflow. COPD mainly involves two related diseases -- chronic bronchitis and emphysema. Both cause chronic obstruction of air flowing through the airways and in and out of the lungs. The obstruction is generally permanent and progresses (becomes worse) over time.
See the entire definition of Chronic obstructive pulmonary disease

Complication: In medicine, an additional problem that arises following a procedure, treatment or illness and is secondary to it. A complication complicates the situation.
See the entire definition of Complication

Condition: The term "condition" has a number of biomedical meanings including the following:

1. An unhealthy state, such as in "this is a progressive condition."
2. A state of fitness, such as "getting into condition."
3. Something that is essential to the occurrence of something else; essentially a "precondition."
4. As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.

See the entire definition of Condition

Congenital: Present at birth. A condition that is congenital is one that is present at birth. There are numerous uses of "congenital" in medicine. There are, for example, congenital abnormalities. (For more examples, see below.)
See the entire definition of Congenital

COPD: Chronic obstructive pulmonary disease . Any disorder that persistently obstructs bronchial airflow. COPD mainly involves two related diseases -- chronic bronchitis and emphysema. Both cause chronic obstruction of air flowing through the airways and in and out of the lungs. The obstruction is generally permanent and progresses (becomes worse) over time.
See the entire definition of COPD

Coronary arteries: The vessels that supply the heart muscle with blood rich in oxygen. They are called the coronary arteries because they encircle the heart in the manner of a crown. The word "coronary" comes from the Latin "corona" and Greek "koron" meaning crown. Like other arteries, the coronaries may be subject to arteriosclerosis (hardening of the arteries). There are a number of coronary arteries. Those most often bypassed today include the right coronary artery, the posterior descending coronary artery, the left main coronary artery, the left anterior descending coronary artery and the left circumflex coronary artery. Plaques obstructing the coronary arteries may also be treated by balloon angioplasty , stents, and other techniques.
See the entire definition of Coronary arteries

Cough: A rapid expulsion of air from the lungs typically in order to clear the lung airways of fluids, mucus, or material. Also called tussis.
See the entire definition of Cough

Cyanosis: A bluish color of the skin and the mucous membranes due to insufficient oxygen in the blood. For example, the lips may show cyanosis. Cyanosis can be evident at birth, as in a "blue baby" who has a heart malformation that permits blood that is not fully oxygenated to enter the arterial circulation. Cyanosis can also appear at any time later in life.
See the entire definition of Cyanosis

Cystic fibrosis : One of the most common grave genetic (inherited) diseases, CF affects the exocrine glands and is characterized by the production of abnormal secretions, leading to mucous build-up.
See the entire definition of Cystic fibrosis

Diabetes: Refers to diabetes mellitus or, less often, to diabetes insipidus . Diabetes mellitus and diabetes insipidus share the name "diabetes" because they are both conditions characterized by excessive urination (polyuria).
See the entire definition of Diabetes

Donor: The giver of a tissue or organ, for example, of blood or a kidney.
See the entire definition of Donor

Dyspnea: Difficult or labored breathing; shortness of breath.
See the entire definition of Dyspnea

Echocardiography: Echocardiography is a diagnostic test which uses ultrasound waves to make images of the heart chambers, valves and surrounding structures. It can measure cardiac output and is a sensitive test for inflammation around the heart ( pericarditis ). It can also be used to detect abnormal anatomy or infections of the heart valves.
See the entire definition of Echocardiography

Edema: The swelling of soft tissues as a result of excess water accumulation.
See the entire definition of Edema

Emergency department: The department of a hospital responsible for the provision of medical and surgical care to patients arriving at the hospital in need of immediate care. Emergency department personnel may also respond to certain situations within the hospital such cardiac arrests.
See the entire definition of Emergency department

Emphysema: 1) A lung condition featuring an abnormal accumulation of air in the lung's many tiny air sacs, a tissue called alveoli. As air continues to collect in these sacs, they become enlarged, and may break, or be damaged and form scar tissue. Emphysema is strongly associated with smoking cigarettes, a practice that causes lung irritation. It can also be associated with or worsened by repeated infection of the lungs, such as is seen in chronic bronchitis. The best response to the early warning signs of emphysema is prevention: stop smoking and get immediate treatment for incipient lung infections. Curing established emphysema is not yet possible. Because patients don't have an adequate amount of space in the lungs to breathe, they gasp for breath, and may not be able to obtain enough oxygen. Those with severe emphysema usually end up using an oxygen machine to breathe. In some cases, medication may be helpful to ease symptoms or to treat infection in already-damaged lungs.
See the entire definition of Emphysema

Essential: 1. Something that cannot be done without.
2. Required in the diet, because the body cannot make it. As in an essential amino acid or an essential fatty acid.
3. Idiopathic. As in essential hypertension. "Essential" is a hallowed term meaning "We don't know the cause."
See the entire definition of Essential

Fatigue: A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.
See the entire definition of Fatigue

Fever : Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
See the entire definition of Fever

Fungal: Pertaining to a fungus . For example, a fungal skin infection.
See the entire definition of Fungal

Gingiva: The gum.
See the entire definition of Gingiva

Heart: The muscle that pumps blood received from veins into arteries throughout the body. It is positioned in the chest behind the sternum (breastbone; in front of the trachea, esophagus, and aorta; and above the diaphragm muscle that separates the chest and abdominal cavities. The normal heart is about the size of a closed fist, and weighs about 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest with the balance in the right chest.
See the entire definition of Heart

Heart attack: The death of heart muscle due to the loss of blood supply. The loss of blood supply is usually caused by a complete blockage of a coronary artery, one of the arteries that supplies blood to the heart muscle. Death of the heart muscle, in turn, causes chest pain and electrical instability of the heart muscle tissue.
See the entire definition of Heart attack

Heart disease: Any disorder that affects the heart. Sometimes the term "heart disease" is used narrowly and incorrectly as a synonym for coronary artery disease . Heart disease is synonymous with cardiac disease but not with cardiovascular disease which is any disease of the heart or blood vessels. Among the many types of heart disease, see, for example: Angina ; Arrhythmia ; Congenital heart disease ; Coronary artery disease ( CAD ); Dilated cardiomyopathy ; Heart attack ( myocardial infarction ); Heart failure ; Hypertrophic cardiomyopathy ; Mitral regurgitation ; Mitral valve prolapse ; and Pulmonary stenosis .
See the entire definition of Heart disease

Heart failure : Inability of the heart to keep up with the demands on it and, specifically, failure of the heart to pump blood with normal efficiency. When this occurs, the heart is unable to provide adequate blood flow to other organs such as the brain, liver and kidneys. Heart failure may be due to failure of the right or left or both ventricles. The signs and symptoms depend upon which side of the heart is failing. They can include shortness of breath (dyspnea), asthma due to the heart (cardiac asthma), pooling of blood (stasis) in the general body (systemic) circulation or in the liver's (portal) circulation, swelling ( edema ), blueness or duskiness (cyanosis), and enlargement (hypertrophy) of the heart.
See the entire definition of Heart failure

Heart muscle: A type of muscle with unique features only found in the heart. The heart muscle, or cardiac muscle, is medically called the myocardium ("myo-" being the prefix denoting muscle).
See the entire definition of Heart muscle

Heart rate: The number of heart beats per unit time, usually per minute. The heart rate is based on the number of contractions of the ventricles (the lower chambers of the heart). The heart rate may be too fast ( tachycardia ) or too slow ( bradycardia ). The pulse is bulge of an artery from the wave of blood coursing through the blood vessel as a result of the heart beat. The pulse is often taken at the wrist to estimate the heart rate.
See the entire definition of Heart rate

Heart transplant: A surgical procedure in which a diseased heart is replaced with a healthy heart from a deceased person.
See the entire definition of Heart transplant

Heart valves: There are four heart valves. All are one-way valves. Blood entering the heart first passes through the tricuspid valve and then the pulmonary valve. After returning from the lungs, the blood passes through the mitral (bicuspid) valve and exits via the aortic valve.
See the entire definition of Heart valves

High blood pressure : Also known as hypertension, high blood pressure is, by definition, a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
See the entire definition of High blood pressure

High blood sugar: An elevated level of the sugar glucose in the blood. Also called hyperglycemia .
See the entire definition of High blood sugar

Hospital: It may seem unnecessary to define a "hospital" since everyone knows the nature of a hospital. A hospital began as a charitable institution for the needy, aged, infirm, or young.
See the entire definition of Hospital

Hypertension: High blood pressure , defined as a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
See the entire definition of Hypertension

Idiopathic: Of unknown cause. Any disease that is of uncertain or unknown origin may be termed idiopathic. For example, acute idiopathic polyneuritis , diffuse idiopathic skeletal hyperostosis , idiopathic pulmonary fibrosis , idiopathic scoliosis , etc.
See the entire definition of Idiopathic

Immune: Protected against infection. The Latin immunis means free, exempt.
See the entire definition of Immune

Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
See the entire definition of Immune system

Immunosuppression: Suppression of the immune system . Immunosuppression may result from certain diseases such as AIDS or lymphoma or from certain drugs such as some of those used to treat cancer . Immunosuppression may also be deliberately induced with drugs, as in preparation for bone marrow or other organ transplantation to prevent the rejection of the transplant .
See the entire definition of Immunosuppression

Immunosuppressive: 1. Pertaining to immunosuppression , the suppression of the immune system .
2. An agent capable of suppressing the immune response .
See the entire definition of Immunosuppressive

Incision: A cut. When making an incision, a surgeon is making a cut.
See the entire definition of Incision

Indication: 1. In medicine, a condition which makes a particular treatment or procedure advisable. CML (chronic myeloid leukemia ) is an indication for the use of Gleevec (imatinib mesylate). 2. A sign or a circumstance which points to or shows the cause, pathology , treatment, or outcome of an attack of disease. The presence of the Philadelphia chromosome in peripheral blood cells is an indication of a relapse in CML.
See the entire definition of Indication

Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
See the entire definition of Infection

Internal medicine: A medical specialty dedicated to the diagnosis and medical treatment of adults. A physician who specializes in internal medicine is referred to as an internist. A minimum of seven years of medical school and postgraduate training are focused on learning the prevention, diagnosis, and treatment of diseases of adults. Subspecialties of internal medicine include allergy and immunology, cardiology (heart), endocrinology (hormone disorders), hematology (blood disorders), infectious diseases, gastroenterology (diseases of the gut), nephrology (kidney diseases), oncology (cancer), pulmonology (lung disorders), and rheumatology ( arthritis and musculoskeletal disorders).
See the entire definition of Internal medicine

Ischemia: Inadequate blood supply (circulation) to a local area due to blockage of the blood vessels to the area.
See the entire definition of Ischemia

Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.

See the entire definition of Kidney

Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."
See the entire definition of Laboratory

Left ventricular assist device: See: Ventricular assist device .
See the entire definition of Left ventricular assist device

Lips: Aside from the lips of the mouth, there are two pairs of lips at the entrance to the vagina . They are the labia majora (the larger outside pair) and the labia minora (the smaller inside pair). Together they form part of the vulva (the female external genitalia ).
See the entire definition of Lips

Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.

See the entire definition of Liver

Lung transplant: The first lung transplant was done by the American surgeon James Hardy (1918-) in 1964.
See the entire definition of Lung transplant

Lungs: The lungs are a pair of breathing organs located with the chest which remove carbon dioxide from and bring oxygen to the blood. There is a right and left lung.
See the entire definition of Lungs

LVAD: Left ventricular assist device. See: Ventricular assist device .
See the entire definition of LVAD

Marrow: The bone marrow .
See the entire definition of Marrow

Medical school: A school with a curriculum leading to a medical degree. The mission of every medical school includes medical teaching, research, and patient care. All medical schools share the goal of preparing students in the art and science of medicine, and providing them with the background necessary to enter the period of graduate medical education. The years of medical school preceding graduate medical education are typically divided into a preclinical phase and a clinical phase.
See the entire definition of Medical school

Medication: 1. A drug or medicine. 2. The administration of a drug or medicine. (Note that "medication" does not have the dangerous double meaning of "drug.")
See the entire definition of Medication

Microscope: An optical instrument that augments the power of the eye to see small objects. The name microscope was coined by Johannes Faber (1574-1629) who in 1628 borrowed from the Greek to combined micro-, small with skopein, to view. Although the first microscopes were simple microscopes, most (if not all) optical microscopes today are compound microscopes.
See the entire definition of Microscope

Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
See the entire definition of Muscle

Nausea: Nausea, is the urge to vomit. It can be brought by many causes including, systemic illnesses, such as influenza , medications, pain, and inner ear disease. When nausea and/or vomiting are persistent, or when they are accompanied by other severe symptoms such as abdominal pain , jaundice , fever, or bleeding, a physician should be consulted.
See the entire definition of Nausea

Operation: Although there are many meanings to the word "operation", in medicine it refers to a surgical procedure.
See the entire definition of Operation

Organ: A relatively independent part of the body that carries out one or more special functions. The organs of the human body include the eye , ear , heart , lungs , and liver .
See the entire definition of Organ

Orthopnea: The inability to breathe easily unless one is sitting up straight or standing erect.
See the entire definition of Orthopnea

Osteoporosis: Thinning of the bones with reduction in bone mass due to depletion of calcium and bone protein . Osteoporosis predisposes a person to fractures, which are often slow to heal and heal poorly. It is more common in older adults, particularly post-menopausal women; in patients on steroids; and in those who take steroidal drugs. Unchecked osteoporosis can lead to changes in posture , physical abnormality (particularly the form of hunched back known colloquially as " dowager's hump "), and decreased mobility.
See the entire definition of Osteoporosis

Oxygen: A colorless, odorless and tasteless gas that makes up about 20% of the air we breathe (and at least half the weight of the entire solid crust of the earth) and which combines with most of the other elements to form oxides. Oxygen is essential to human, animal and plant life.
See the entire definition of Oxygen

PA-C: Physician Assistant - Certified.
See the entire definition of PA-C

Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
See the entire definition of Pain

Pharmacy: A location where prescription drugs are sold. A pharmacy is, by law, constantly supervised by a licensed pharmacist.
See the entire definition of Pharmacy

Postoperative: After surgery. As opposed to preoperative, before surgery.
See the entire definition of Postoperative

Primary: First or foremost in time or development. The primary teeth (the baby teeth) are those that come first. Primary may also refer to symptoms or a disease to which others are secondary.
See the entire definition of Primary

Primary care: The "medical home" for a patient, ideally providing continuity and integration of health care. All family physicians and most pediatricians and internists are in primary care. The aims of primary care are to provide the patient with a broad spectrum of care, both preventive and curative, over a period of time and to coordinate all of the care the patient receives.
See the entire definition of Primary care

Primary care provider: In insurance parlance, a physician chosen by or assigned to a patient, who both provides primary care and acts as a gatekeeper to control access to other medical services.
See the entire definition of Primary care provider

Pulmonary: Having to do with the lungs. (The word comes from the Latin pulmo for lung).
See the entire definition of Pulmonary

Pulmonary fibrosis: Scarring throughout the lungs which can be caused by many conditions such as, sarcoidosis , hypersensitivity pneumonitis , asbestosis, and certain medications. Pulmonary fibrosis can also occur without an identifiable cause, in which case it is referred to as idiopathic pulmonary fibrosis . Symptoms include shortness of breath, coughing and diminished exercise tolerance. Treatment involves the use of corticosteroids (such as prednisone ) and/or other medications that suppress the body's immune system. Interferon gamma-1b treatment may help patients with idiopathic pulmonary fibrosis who do not respond to corticosteroid therapy. The goal of treatment is to decrease lung inflammation and subsequent scarring. Responses to treatment vary. Toxicity and side effects of treatments can be serious. Therefore, patients with pulmonary fibrosis are generally cared for by lung specialists.
See the entire definition of Pulmonary fibrosis

Pulmonary hypertension : High blood pressure in the pulmonary artery that conveys blood from the right ventricle to the lungs. The pressure in the pulmonary artery is normally low compared to that in the aorta . Pulmonary hypertension can irrevocably damage the lungs and cause failure of the right ventricle.
See the entire definition of Pulmonary hypertension

Pus: A thick whitish-yellow fluid which results from the accumulation of white blood cells (WBCs), liquified tissue and cellular debris. Pus is commonly a site of infection or foreign material in the body.
See the entire definition of Pus

Recurrent: Back again. A recurrent fever is a fever that has returned after an intermission: a recrudescent fever.
See the entire definition of Recurrent

Rehabilitation: The process of restoration of skills by a person who has had an illness or injury so as to regain maximum self-sufficiency and function in a normal or as near normal manner as possible. For example, rehabilitation after a stroke may help the patient walk again and speak clearly again.
See the entire definition of Rehabilitation

Rejection: In transplantation biology, the refusal by the body to accept transplanted cells, tissues or organs. For example, a kidney transplanted may be rejected.
See the entire definition of Rejection

Rest: 1. Repose. Relaxation.
2. A fragment of embryonic tissue that has been retained after the period of embryonic development. Also called an embryonic rest.
See the entire definition of Rest

Rheumatic fever: An illness that occurs following a streptococcus infection (such as a "strep throat") or scarlet fever and predominantly affects children. Symptoms include fever, pain in the joints, nausea, stomach cramps, and vomiting. Rheumatic fever can cause long-lasting effects in the skin, joints, heart, and brain.
See the entire definition of Rheumatic fever

Sirolimus: A naturally occurring substance discovered in a soil sample from Easter Island. Sirolimus was initially thought to hold promise as an antifungal antibiotic but this idea was dropped when sirolimus was unexpectedly found to have immunosuppressive activity. The US Food and Drug Administration in 1999 approved the use of sirolimus as an immunosuppressant agent. But earlier in the nineties, evidence had been uncovered that sirolimus was also a potent inhibitor of the growth of smooth muscle cells in blood vessels. The idea was then "hatched" that sirolimus might be used to inhibit the restenosis (reclosure) of coronary arteries. (Today, after a balloon angioplasty has been done to open a clogged coronary artery, a mesh tube called a stent is often inserted to keep the artery open. However, restenosis occurs in up to a third of cases when smooth muscle cells migrate from the vessel wall into the stent. The muscle cells proliferate there and narrow the interior diameter of the stent.) To prevent restenosis, stents coated, or "medicated", with sirolimus came into use. The sirolimus is eluted continuously from the stent and deters or slows restenosis.
See the entire definition of Sirolimus

Skin: The skin is the body's outer covering. It protects us against heat and light, injury, and infection. It regulates body temperature and stores water, fat, and vitamin D. Weighing about 6 pounds, the skin is the body's largest organ. It is made up of two main layers; the outer epidermis and the inner dermis.

See the entire definition of Skin

Sputum: The mucus and other matter brought up from the lungs , bronchi , and trachea that one may cough up and spit out or swallow. The word "sputum" is borrowed directly from the Latin "to spit." Called also expectoration.
See the entire definition of Sputum

Stomach: 1. The sac-shaped digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine.
See the entire definition of Stomach

Stool: The solid matter discharged in a bowel movement.
See the entire definition of Stool

Stroke : The sudden death of some brain cells due to a lack of oxygen when the blood flow to the brain is impaired by blockage or rupture of an artery to the brain. A stroke is also called a cerebrovascular accident or, for short, a CVA.
See the entire definition of Stroke

Surgeon: A physician who treats disease, injury, or deformity by operative or manual methods. A medical doctor specialized in the removal of organs, masses and tumors and in doing other procedures using a knife (scalpel). The definition of a "surgeon" has begun to blur in recent years as surgeons have begun to minimize the cutting, employ new technologies that are "minimally invasive," use scopes, etc.
See the entire definition of Surgeon

Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
See the entire definition of Surgery

Symptom: Any subjective evidence of disease. Anxiety, lower back pain , and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.
See the entire definition of Symptom

Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
See the entire definition of Syndrome

Tacrolimus: A drug that suppresses the immune system and prevents transplant rejection . The drug acts by inhibiting the activation of T cells .
See the entire definition of Tacrolimus

Therapy: The treatment of disease .
See the entire definition of Therapy

Tiredness: See: Tired .
See the entire definition of Tiredness

Tissue: A tissue in medicine is not like a piece of tissue paper. It is a broad term that is applied to any group of cells that perform specific functions. A tissue in medicine need not form a layer. Thus,

• The bone marrow is a tissue;
• Connective tissue consists of cells that make up fibers in the framework supporting other body tissues; and
• Lymphoid tissue is the part of the body's immune system that helps protect it from bacteria and other foreign entities.

See the entire definition of Tissue

Transplant: The grafting of a tissue from one place to another, just as in botany a bud from one plant might be grafted onto the stem of another. The transplanting of tissue can be from one part of the patient to another (autologous transplantation), as in the case of a skin graft using the patient's own skin; or from one patient to another (allogenic transplantation), as in the case of transplanting a donor kidney into a recipient.
See the entire definition of Transplant

Tremor: Any abnormal repetitive shaking movement of the body. Tremors have many causes and can be inherited, be related to illnesses such as thyroid disease, or caused by fever , hypothermia, drugs or fear.
See the entire definition of Tremor

UNOS: Acronym for the United Network for Organ Sharing, the nationwide umbrella for transplantation organ sharing in the U.S.
See the entire definition of UNOS

Urine: Liquid waste. The urine is a clear, transparent fluid. It normally has an amber color. The average amount of urine excreted in 24 hours is from 40 to 60 ounces (about 1,200 cubic centimeters). Chemically, the urine is mainly an aqueous (watery) solution of salt (sodium chloride) and substances called urea and uric acid. Normally, it contains about 960 parts of water to 40 parts of solid matter. Abnormally, it may contain sugar (in diabetes), albumen (a protein) (as in some forms of kidney disease), bile pigments (as in jaundice ), or abnormal quantities of one or another of its normal components.
See the entire definition of Urine

Ventricular: Pertaining to the ventricles, the lower chambers of the heart , as in ventricular fibrillation and ventricular septal defect .
See the entire definition of Ventricular

Ventricular assist device: A mechanical pump that takes over the function of the damaged ventricle of the heart and restores normal blood flow.
See the entire definition of Ventricular assist device

Wheezing: A whistling noise in the chest during breathing when the airways are narrowed or compressed.
See the entire definition of Wheezing

White blood cell: One of the cells the body makes to help fight infections. There are several types of white blood cells ( leukocytes ). The two most common types are the lymphocytes and neutrophils (also called polymorphonuclear leukocytes, PMNs, or "polys").
See the entire definition of White blood cell

White blood cell count (leukocyte count): The number of white blood cells (WBCs) in the blood. The WBC is usually measured as part of the CBC ( complete blood count ). White blood cells are the infection-fighting cells in the blood and are distinct from the red (oxygen-carrying) blood cells known as erythrocytes. There are different types of white blood cells, including neutrophils (polymorphonuclear leukocytes ; PMNs), band cells (slightly immature neutrophils), T-type lymphocytes (T cells), B-type lymphocytes (B cells), monocytes, eosinophils, and basophils. All the types of white blood cells are reflected in the white blood cell count. The normal range for the white blood cell count varies between laboratories but is usually between 4,300 and 10,800 cells per cubic millimeter of blood. This can also be referred to as the leukocyte count and can be expressed in international units as 4.3 - 10.8 x 109 cells per liter.
See the entire definition of White blood cell count

Most Popular Topics

Explore 80+ Centers

Search Medical Dictionary

or A-Z List

We subscribe to the HONcode principles. Verify here.

©2008 WebMD, Inc. All rights reserved.
eMedicineHealth does not provide medical advice, diagnosis or treatment. See Additional Information.