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February 6, 2012
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Hemophilia

Medical Author:
Troy S Cutler, MD
Medical Editor:
Melissa Conrad Stöppler, MD, Chief Medical Editor
Melissa Conrad Stöppler, MD, Chief Medical Editor
Melissa Conrad Stöppler, MD, Chief Medical Editor

Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

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Hemophilia Overview

Hemophilia is an inherited bleeding disorder. The blood of someone with hemophilia will not clot normally. Bleeding may occur spontaneously or following injury.

Hemophiliaoccurs in 2 forms, hemophilia A and B. In both forms, a gene is defective. The defective gene interferes with the ability of the body to produce the clotting factors that allow for normal clotting. The result is a tendency for abnormal, excessive bleeding.

  • Hemophilia A occurs in 1 in 10,000 people. Hemophilia B occurs in 1 in 40,000.

  • With either disorder, you may show a mild form in which bleeding occurs only under severe stress, such as major injury.

    • Moderate cases rarely will have spontaneous bleeding but will bleed after surgery or trauma.

    • Severe cases will exhibit spontaneous bleeding-that is, bleeding without any recognizable trauma. Spontaneous bleeding can occur in any part of your body, but it is usually in the joints of the fingers, wrists, feet, and spine.
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Hemophilia

Black Eye »

Black Eye Overview

A black eye is a relatively common result of injury to the face or the head, caused when blood and other fluids collect in the space around the eye; swelling and dark discoloration result-hence, the name "black eye."

Most black eyes are relatively minor injuries. Many heal on their own in a few days; however, sometimes they signify a more serious injury.

Despite the name, "black eye," the eye itself is not usually injured. The tissues around the eye may be significantly discolored and swollen without any injury to the eye itself. Think of it as a bruise around the eye.

Like a bruise, as a black eye heals, the swelling around the eye decreases, and the bruise gradually fades away.

  • The skin around the eye is very loose, with mostly fat underneath. This makes it an ideal site for fluid to accumulate. The effects of gravity also help to swellÂthis part of the face. This is why many people wake up with "pu...

Read the Black Eye article »


Read What Your Physician is Reading on Medscape

Hemophilia »

Hemophilia A(HA), which comprises approximately 80% of cases,is considered the classic form of hemophilia, and hemophilia B (HB) is termed Christmas disease.

Read More on Medscape Reference »

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