Hemophilia: Treatment for People Who Have Inhibitors
What are inhibitors?
Some people who have hemophilia A develop antibodies to the injected clotting factor. The body thinks that the replacement clotting factors don't belong in the body, so it creates the antibodies, also called inhibitors, to get rid of them.
Some people produce few inhibitors; others produce many.
How can I be treated?
If you have inhibitors, hemophilia treatment may require specially engineered replacement clotting factors. Other treatment for clotting factor inhibitors includes therapy to suppress the immune system (immunosuppressive therapy).
If you have a larger amount of inhibitors, you might be treated with:
If your body produces few inhibitors in reaction to clotting factors, you may be treated with clotting factor concentrate that is made in a lab (recombinant clotting factors). You might get large doses of the clotting factors, which can overwhelm the inhibitors.
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