Hemophilia: Treatment for People With Inhibitors
What are inhibitors?
Some people who have hemophilia A develop antibodies to the injected clotting factor. The body thinks that the replacement clotting factors don't belong in the body, so it creates the antibodies, also called inhibitors, to get rid of them.
Some people produce few inhibitors; others produce many.
How can I be treated?
If you have inhibitors, hemophilia treatment may require specially engineered replacement clotting factors. Other treatment for clotting factor inhibitors includes therapy to suppress the immune system (immunosuppressive therapy).
If you have a larger amount of inhibitors, you might be treated with:
If your body produces few inhibitors in reaction to clotting factors, you may use the treatments above. You also may be treated with:
If your body produces many inhibitors, you may be treated by pumping your blood through a machine that removes or neutralizes the inhibitors (plasmapheresis) to reduce or neutralize the inhibitors in the body. This process only works temporarily and is used before a surgery or after a major injury.
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