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Histoplasmosis (cont.)

Histoplasmosis Prognosis

About 90% of patients that acquire acute pulmonary histoplasmosis are asymptomatic and about another 5%-7% who develop symptoms recover completely so the prognosis or outcomes are good for the majority of patients. Few may get acute pericarditis and pleural effusions. As the severity of the disease increases, the prognosis decreases from fair to poor. Chronic pulmonary histoplasmosis patients usually develop (90%) cavities in the lungs that may reduce lung capacity and result in respiratory problems that increase chances for secondary lung infections. Progressive disseminated histoplasmosis has a grim prognosis (death in a few weeks to months) if not appropriately treated. Even with appropriate treatment, some patients will experience relapses and may require antifungal medication for the rest of their life.

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