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February 8, 2012
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Hives and Angioedema

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Hives and Angioedema Overview

Hives is an allergic skin reaction that comes on suddenly. The hives themselves are slightly raised, smooth, flat-topped bumps called wheals and welts that are usually slightly more reddish in color than the surrounding skin and cause severe itching. Hives look somewhat like mosquito bites.

Angioedema is like hives, only the welts are larger and form at a deeper layer in the skin. Angioedema causes severe swelling, usually in the face, near the eyes and mouth. The swelling can also occur in the inside of the throat, which is a dangerous situation because it can close off the passage of air into the lungs.

Hives and angioedema can occur together, but they usually do not. Hives is the most common rash for which people seek emergency medical care. One of every five people will have hives at some time in their lives. Angioedema is less common. Hives and angioedema can happen at any age.

The medical term for hives is urticaria.

This article does not refer to an uncommon and more serious condition, hereditary angioedema. Hereditary angioedema involves swelling over the entire body, including some internal organs.

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Hives and Angioedema

Allergic Reaction Overview

An allergic reaction is the body's way of responding to an "invader." When the body senses a foreign substance, called an antigen, the immune system is triggered. The immune system normally protects the body from harmful agents such as bacteria and toxins. Its overreaction to a harmless substance (an allergen) is called a hypersensitivity reaction, or an allergic reaction.

  • Anything can be an allergen. Dust, pollen, plants, medications, (such as ibuprofen, sulfa drugs like sulfamethoxazole and trimethoprim [Bactrim], codeine, amoxicillin [Amoxil, Amoxil Pediatric Drops, Moxatag, Trimox]), foods (common food allergies include shrimp and other shellfish, peanuts), insect bites (such as from mosquitos or bees), animal dander, viruses, or bacteria are examples of allergens.
  • Reactions may occur in one spot, such as a small localized skin rash, itchy eyes, face bumps, or all over, as in a whole body rash such as ...

Read the Allergic Reaction article »


Read What Your Physician is Reading on Medscape

Angioedema »

Angioedema is a subcutaneous extension of urticaria, resulting in deep swelling within subcutaneous sites.

Read More on Medscape Reference »

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