Hives and Angioedema (cont.)
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Hives and Angioedema Causes
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Hives and angioedema are reactions of the skin to histamine and other chemicals such as bradykinin, leukotriene C4, and prostaglandin D2. These chemicals act on blood vessels and other tissues to produce the clinical signs of hives and angioedema. This process is often, although not always, due to an allergic reaction.
There are many causes of hives and angioedema. At least half the time, the specific cause cannot be determined. When the cause of a medical condition is not known, it is termed idiopathic. Idiopathic hives and angioedema are very common.
Some of the more common triggers include the following:
Chronic hives are hives that lasts longer than six weeks. This can happen to anyone, but it is most common in women who are 40-60 years of age. Chronic hives can last for months or even years, but this is unusual.
Medically Reviewed by a Doctor on 6/4/2014
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