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Homocysteine (cont.)

Who should have their homocysteine levels tested?

Infants blood and urine are often checked for elevated homocysteine levels if they have a family history of the disease, or if they have certain medical conditions including eye lens dislocations, unusual (Marfan type) body shape, mental retardation, or signs of stroke.

Younger adults who have an early heart attack, stroke, or blood clots are often screened for blood clotting abnormalities including homocysteine blood tests.

Homocysteine levels are also often measured when a patient suffers a heart attack or stroke and has no risk factors for that illness (smoking, high blood pressure, high cholesterol, diabetes).

At present it is not recommended that individuals consuming normal diets with adequate folate levels be screened for elevated homocysteine levels.


Haque WM. Homocysteine and Pregnancy. Best Pract Res Clin Obstet Gynaecol. 2003 Jun;17(3):459-69

Saposnik G; Ray JG; Sheridan P; McQueen M; Lonn E. Homocysteine-lowering therapy and stroke risk, severity, and disability: additional findings from the HOPE 2 trial. Stroke. 2009; 40(4):1365-72

Medically Reviewed by a Doctor on 2/22/2016

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