Medications

GENERIC NAME: HYALURONATE - INJECTION (hi-uh-LYOU-ron-ate)
BRAND NAME(S): Hyalgan, Synvisc
Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
USES: This medication is used to treat arthritis of the knee. It should be used only after non-drug treatment and simple medication (e.g., acetaminophen) have failed to provide relief.
HOW TO USE: This drug is given by injection into the affected joint by your doctor once a week. Complete the full treatment course, even if you are already feeling better. Follow all instructions. You may not feel clear pain relief until after the last injection in the series.
SIDE EFFECTS: Injection site pain, itching, swelling, heat or redness of the joint or headache may occur. If these persist or worsen, notify your doctor. Very unlikely but report promptly: fever, bruising, rapid heartbeat, sweating, fainting, chest or stomach pressure/pain, redness of the hands or feet. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Before using this drug, tell your doctor your medical history, including: allergies (especially drug allergies), infections and skin diseases in the area of the injection site, knee joint infections. Avoid heavy physical activity or prolonged use of the affected joint (such as jogging, tennis) within 48 hours following the injection. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this drug is excreted into breast milk. Consult your doctor before breast-feeding.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Back to Medications Index

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