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Hyperthyroidism (cont.)

Antithyroid Medications

  • Effect: Decreased thyroid hormone production
  • Indications:
    • Hyperthyroidism from multiple causes
    • Low doses of methimazole (<10-15mg/day) are safe in pregnancy or postpartum in a woman breastfeeding
    • Elderly persons or cardiac patients requiring 'pretreatment' with antithyroid medications before radioiodine therapy
  • Risks :
    • Skin rashes, agranulocytosis (compromised immune system), and hepatitis
    • Increased risk of liver failure. FDA black box warnings restricts use of PTU to those patients who cannot tolerate methimazole or are in the first trimester of pregnancy.
Medically Reviewed by a Doctor on 11/10/2014
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Read What Your Physician is Reading on Medscape

Hyperthyroidism »

Thyrotoxicosis is the hypermetabolic condition associated with elevated levels of free thyroxine (FT4), free triiodothyronine (FT3), or both.

Read More on Medscape Reference »

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