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February 10, 2012
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Hyperthyroidism (cont.)

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Hyperthyroidism as a Result of Other Medical Treatments

Amiodarone therapy

  • Amiodarone is a drug used in the treatment of abnormal heart rhythms. Amiodarone tablets (Cordarone, Pacerone) contain iodine, and up to 10% of people taking this medication develop abnormalities in thyroid function.
    • Patients taking amiodarone should have baseline thyroid function tests before starting amiodarone therapy
    • Type 1 amiodarone-induced hyperthyroidism (Jod-Basedow phenomenon) causes an increased production of thyroid hormones due to the iodine portion of amiodarone
    • Type 2 amiodarone-induced hyperthyroidism resembles a destructive thyroiditis, where increased amounts of thyroid hormone are released

IV contrast agents for CT scans

  • Excess iodine in the contrast material used for CT scans may cause an increased production of thyroid hormone.
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Read What Your Physician is Reading on Medscape

Hyperthyroidism »

Thyrotoxicosis is the hypermetabolic condition associated with elevated levels of free thyroxine (FT4), free triiodothyronine (FT3), or both.

Read More on Medscape Reference »

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