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Hypopituitarism in Children (cont.)

Hypopituitarism Treatment

Patient Comments

Treatment primarily involves hormone replacement therapy.

Medications

Drugs used to treat hypopituitarism replace the deficient hormone.

  • Somatotropin (recombinant human growth hormone) is used to treat growth hormone deficiency. This therapy is used to treat growth failure and metabolic abnormalities related to growth hormone deficiency. The treatment (growth) response in infants and children with severe growth hormone deficiency as a result of hypopituitarism is remarkable.
  • Levothyroxine (Synthroid, Levoxyl) is used to treat low levels of thyroid hormone. Thyroid hormone is needed for normal growth, metabolism, and nervous system development.
  • Hydrocortisone (Cortef, Solu-Cortef) and fludrocortisone (Florinef) are used to treat adrenal insufficiency resulting from ACTH deficiency or primary disorders of the adrenal gland.
  • Vasopressin (Pitressin) or desmopressin (DDAVP) may be used to treat diabetes insipidus (ADH deficiency).

Hypopituitarism Surgery

Surgery may be performed if a tumor is present within or near the pituitary gland, depending on the type and location of the tumor, and depending on the symptoms being experienced.

Hypopituitarism Follow-up

The doctor or health care practitioner may schedule routine checkups every three months to monitor growth and development.

Frequent checkups for children on growth hormone replacement therapy may be scheduled to monitor progress and side effects.

A doctor who specializes in studying hormones (a pediatric endocrinologist) should supervise the treatment of children with hypopituitarism.

Outlook for Hypopituitarism

With appropriate treatment, the prognosis is very good.

Web Links

The Magic Foundation

The Hormone Foundation

John A. Seibel, MD; Board Certified Internal Medicine with a subspecialty in Endocrinology & Metabolism

REFERENCE:

"Causes and clinical manifestations of central adrenal insufficiency in children"
UpToDate.com


Medically Reviewed by a Doctor on 12/24/2015

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Patient Comments & Reviews

The eMedicineHealth doctors ask about Hypopituitarism in Children:

Hypopituitarism in Children - Symptoms

What symptoms of hypopituitarism did your child experience?

Hypopituitarism in Children - Medical Treatment

What what your child's experience with hormone replacement therapy? Please describe.


Read What Your Physician is Reading on Medscape

Hypopituitarism »

Hypopituitarism is a partial or complete insufficiency of pituitary hormone secretion, which may derive from pituitary or hypothalamic disease.

Read More on Medscape Reference »


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