Hypopituitarism is a condition in which the pituitary gland (a small gland at the base of the brain) does not produce one or more of its hormones or not enough of them. This condition may occur because of disease in the pituitary or hypothalamus (a part of the brain that contains hormones that control the pituitary gland). When there is low or no production of all the pituitary hormones, the condition is called panhypopituitarism. This condition may affect either children or adults.
The pituitary gland sends signals to other glands (eg, thyroid gland) to produce hormones (eg, thyroid hormone). The hormones produced by the pituitary gland and other glands have a significant impact on the body’s functions, such as growth, reproduction, blood pressure, and metabolism (the physical and chemical processes of the body). When one or more of these hormones is not produced properly, the body’s normal functions can be affected. Some of the hormones like cortisol and thyroid hormone may require prompt treatment, whereas others may not be life threatening.
The pituitary gland produces several hormones. Some of the important hormones are as follows:
In hypopituitarism, one or more of these pituitary hormones is missing. The lack of hormone results in a loss of function of the gland or organ that it controls.
Medically Reviewed by a Doctor on 7/30/2014
James R Mulinda, MD, FACP, FACE
Arthur B Chausmer, MD, PhD, FACP, FACE, FACN, CNS
Francisco Talavera, PharmD, PhD
George T Griffing, MD
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