Some persons may have no symptoms or a gradual onset of symptoms. In other persons, the symptoms may be sudden and dramatic. The symptoms depend on the cause, rapidity of onset, and the hormone that is involved.
- ACTH deficiency: Symptoms include fatigue, low blood pressure, weight loss, weakness, depression, nausea, or vomiting.
- TSH deficiency: Symptoms include constipation, weight gain, sensitivity to cold, decreased energy, and muscle weakness or aching.
- FSH and LH deficiency: In women, symptoms include irregular or stopped menstrual periods and infertility. In men, symptoms include loss of body and facial hair, weakness, lack of interest in sexual activity, erectile dysfunction, and infertility.
- GH deficiency: In children, symptoms include short height, fat around the waist and in the face, and poor overall growth. In adults, symptoms include low energy, decreased strength and exercise tolerance, weight gain, decreased muscle mass, and feelings of anxiety or depression.
- Prolactin deficiency: In women, symptoms include lack of milk production, fatigue, and loss of underarm and pubic hair. No symptoms are seen in men.
- ADH deficiency: Symptoms include increased thirst and urination.
James R Mulinda, MD, FACP, FACE
Arthur B Chausmer, MD, PhD, FACP, FACE, FACN, CNS
Francisco Talavera, PharmD, PhD
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