Angiokeratomas are telangiectasias with keratotic elements. They present in different clinical scenarios including (a) solitary or multiple angiokeratomas occurring predominantly on lower extremities; (b) angiokeratoma of Fordyce affecting the scrotum and the vulva; (c) angiokeratoma of Mibelli, an autosomal dominant disorder affecting dorsum of hands and feet, elbows, and knees;(d) angiokeratoma corporis diffusum associated with Fabry’s disease, an X-linked recessive disorder characterized by a-galactosidase-A deficiency and affecting the lower abdomen, buttocks, and genitalia; and (e) angiokeratoma circumscriptum usually grouped on one extremity.

In this photo is an angiokeratoma on the thigh of a young child.