Immunization Schedule, Children Glossary of Medical Terms

These are medical definitions of medical terms from the MedTerms.com medical dictionary that appear in the Immunization Schedule, Children article.

Acellular: Not made up of cells or divided into cells. Or lacking intact cells as, for example, an acellular vaccine which may contain cellular material but not complete cells.
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Aggressive: In oncology, quickly growing, tending to spread rapidly. As, for example, an aggressive tumor.
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American Academy of Pediatrics: AAP. Its member pediatricians "dedicate their efforts and resources to the health, safety and well-being of infants, children, adolescents and young adults." According to the Academy, it had as of 1998 some 53,000 members in the United States, Canada and Latin America. Over 34,000 of them were board-certified and called Fellows of the American Academy of Pediatrics (FAAP).
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Anemia: The condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin in the blood. The oxygen-carrying capacity of the blood is, therefore, decreased.
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Arms: An appendage in anatomy and in clinical trials . See: Arm .
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Aspirin: A good example of a tradename that entered into the language, Aspirin was once the Bayer trademark for acetylsalicylic acid .
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Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
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Bacterial: Of or pertaining to bacteria . For example, a bacterial lung infection .
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Bacterium: The singular of bacteria .
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Blood: The familiar red fluid in the body that contains white and red blood cells , platelets , proteins , and other elements. The blood is transported throughout the body by the circulatory system . Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.
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Brain: That part of the central nervous system that is located within the cranium ( skull ). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."
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Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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CDC: The Centers for Disease Control and Prevention , the US agency charged with tracking and investigating public health trends. The stated mission of the CDC is "To promote health and quality of life by preventing and controlling disease, injury, and disability." The CDC is a part of the U.S. Public Health Services (PHS) under the Department of Health and Human Services (HHS).
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Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane .
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Centers for Disease Control and Prevention: The US agency charged with tracking and investigating public health trends. The stated mission of the Centers for Disease Control and Prevention, commonly called the CDC, is "To promote health and quality of life by preventing and controlling disease, injury, and disability."
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Cervical: Having to do with any kind of neck including the neck on which the head is perched and the neck of the uterus. The word "cervix" in Latin means "neck". That is why cervical vertebrae and cervical cancer involve quite disparate parts of the anatomy joined only by the meaning of the word "cervix".
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Cervical cancer: Cancer of the entrance to the womb (uterus). The cervix is the lower, narrow part of the uterus (womb). The uterus, a hollow, pear-shaped organ, is located in a woman's lower abdomen, between the bladder and the rectum. The cervix forms a canal that opens into the vagina, which leads to the outside of the body.

Regular pelvic exams and Pap testing can detect precancerous changes in the cervix. Precancerous changes in the cervix may be treated with cryosurgery, cauterization, or laser surgery. The most common symptom of cancer of the cervix is abnormal bleeding. Cancer of the cervix can be diagnosed using a Pap test or other procedures that sample the cervix tissue. Cancer of the cervix requires different treatment than cancer that begins in other parts of the uterus.
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Cervix: The cervix is the lower, narrow part of the uterus (womb). The uterus, a hollow, pear-shaped organ, is located in a woman's lower abdomen, between the bladder and the rectum. The cervix forms a canal that opens into the vagina, which leads to the outside of the body.

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Chickenpox: A highly infectious viral disease also known medically as varicella -- in many countries, this disease is always called "varicella" -- that causes a blister-like rash, itching, fatigue and fever. The rash crops up first on the face and trunk and can spread over the entire body resulting in 250 to 500 itchy blisters.

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Childhood: (1) The time for a boy or girl from birth until he or she is an adult. (2) The more circumscribed period of time from infancy to the onset of puberty .
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Children's immunizations : In the United States, it is recommended that all children receive vaccination against:

Hepatitis B
Diphtheria, tetanus , pertussis
Haemophilus influenzae type B (HIB)
Poliovirus
Measles , mumps , rubella
Varicella zoster virus ( chickenpox ).

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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Chronic disease: A disease that persists for a long time. A chronic disease is one lasting 3 months or more, by the definition of the U.S. National Center for Health Statistics. Chronic diseases generally cannot be prevented by vaccines or cured by medication, nor do they just disappear. Eighty-eight percent of Americans over 65 years of age have at least one chronic health condition (as of 1998). Health damaging behaviors - particularly tobacco use, lack of physical activity, and poor eating habits - are major contributors to the leading chronic diseases.
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Clinical trials: Trials to evaluate the effectiveness and safety of medications or medical devices by monitoring their effects on large groups of people.
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Coma: A state of deep unarousable unconsciousness.
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Cough: A rapid expulsion of air from the lungs typically in order to clear the lung airways of fluids, mucus, or material. Also called tussis.
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Department of Health and Human Services : The United States government's principal agency for "protecting the health of all Americans and providing essential human services, especially for those who are least able to help themselves." Also known as DHHS and HHS.
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Diarrhea : A familiar phenomenon with unusually frequent or unusually liquid bowel movements, excessive watery evacuations of fecal material. The opposite of constipation . The word "diarrhea" with its odd spelling is a near steal from the Greek "diarrhoia" meaning "a flowing through." Plato and Aristotle may have had diarrhoia while today we have diarrhea. There are myriad infectious and noninfectious causes of diarrhea.
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Diphtheria: An acute infectious disease that typically strikes the upper respiratory tract including the throat. It is caused by infection with the bacteria Corynebacterium diphtheriae. Symptoms include sore throat and mild fever at first. As the disease progresses, a membranous substance forms in the throat that makes it difficult to breathe and swallow.
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Discharge: 1.The flow of fluid from part of the body, such as from the nose or vagina.
2. The passing of an action potential, such as through a nerve or muscle fiber .
3. The release of a patient from a course of care. The doctor may then dictate a discharge summary.
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DTaP: Diphtheria-Tetanus-acellular Pertussis vaccine.
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Endocrinology: The study of hormones , their receptors , the intracellular signalling pathways they invoke, and the diseases and conditions associated with them.
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Epidemic: The occurrence of more cases of a disease than would be expected in a community or region during a given time period. A sudden severe outbreak of a disease such as SARS. From the Greek "epi-", "upon" + "demos", "people or population" = "epidemos" = "upon the population." See also: Endemic; Pandemic.
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FDA: The Food and Drug Administration, an agency within the U.S. Public Health Service, which is a part of the Department of Health and Human Services.
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Fever : Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
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Flu: Short for influenza . The flu is caused by viruses that infect the respiratory tract which are divided into three types, designated A, B, and C. Most people who get the flu recover completely in 1 to 2 weeks, but some people develop serious and potentially life-threatening medical complications, such as pneumonia . Much of the illness and death caused by influenza can be prevented by annual influenza vaccination.
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Flu vaccine: The flu vaccination ( influenza ) is recommended for persons at high risk for serious complications from influenza virus infection.
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FluMist: FluMist™. See: Nasal flu vaccine .
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Food and Drug Administration: The FDA, an agency within the U.S. Public Health Service, which is a part of the Department of Health and Human Services.
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Gastroenteritis: Inflammation of the stomach and the intestines. Can cause nausea and vomiting and/or diarrhea . Gastroenteritis has numerous causes: including infectious organisms (viruses, bacteria, etc.), food poisoning , and stress.
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Genital: Pertaining to the external and internal organs of reproduction. (Not to be confused with genetic.)
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Health and Human Services : The United States government's principal agency for "protecting the health of all Americans and providing essential human services, especially for those who are least able to help themselves." Also known as DHHS and HHS.
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Hepatitis: Inflammation of the liver from any cause.
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Hepatitis A: Inflammation of the liver caused by the hepatitis A virus (HAV). HAV is usually transmitted from person to person by food or drink that has been contaminated with the stool of a person with hepatitis A. This type of transmission is called "fecal-oral." The virus is more easily spread in areas where there are poor sanitary conditions or where good personal hygiene is not observed. In 2003 there were hepatitis A outbreaks in the US associated with eating raw or lightly cooked green onions (scallions). Casual contact, as in a school, office, or another work setting, does not spread the virus.
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Hepatitis B: Inflammation of the liver due to the hepatitis B virus (HBV), once thought to be passed only through blood products. It is now known that hepatitis B can also be transmitted via needle sticks, body piercing and tattooing using un sterilized instruments, the dialysis process, sexual and even less intimate close contact, and childbirth. Symptoms include fatigue, jaundice , nausea, vomiting, dark urine, light stools. Diagnosis is by blood test. Treatment is via anti-viral drugs and/or hepatitis B immunoglobulin (HBIG).
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HIB: Abbreviation for Haemophilus influenzae type B .
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Hospital: It may seem unnecessary to define a "hospital" since everyone knows the nature of a hospital. A hospital began as a charitable institution for the needy, aged, infirm, or young.
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HPV: See: Human papillomavirus .
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Human papillomavirus: HPV. A family of over 100 viruses including those which cause warts and are transmitted by contact. Some types of HPV are associated with tumors of the genital tract including, notably, cancer of the cervix.
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Immune: Protected against infection. The Latin immunis means free, exempt.
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Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
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Immunization: Vaccination. Immunizations work by stimulating the immune system, the natural disease-fighting system of the body. The healthy immune system is able to recognize invading bacteria and viruses and produce substances (antibodies) to destroy or disable them. Immunizations prepare the immune system to ward off a disease. To immunize against viral diseases, the virus used in the vaccine has been weakened or killed. To immunize against bacterial diseases, it is generally possible to use only a small portion of the dead bacteria to stimulate the formation of antibodies against the whole bacteria. In addition to the initial immunization process, it has been found that the effectiveness of immunizations can be improved by periodic repeat injections or "boosters." Also see Immunizations (in the plural) and Immunization of a specific type (such Immunization, Polio).
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Infant: A child up to 2 years (24 months) of age.
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Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Influenza: The flu is caused by viruses that infect the respiratory tract which are divided into three types, designated A, B, and C. Most people who get the flu recover completely in 1 to 2 weeks, but some people develop serious and potentially life-threatening medical complications, such as pneumonia . Much of the illness and death caused by influenza can be prevented by annual influenza vaccination.
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Intestine: The long, tubelike organ in the abdomen that completes the process of digestion. It consists of the small and large intestines.
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Intussusception : Telescoping (prolapse) of a portion of the intestine within another immediately adjacent portion of intestine. This decreases the supply of blood to the affected part of the intestine, and frequently leads to intestinal obstruction. The pressure created by the two walls of the intestine pressing together causes inflammation, swelling, and reduces the blood flow. Death of bowel tissue can occur, with significant bleeding, perforation, abdominal infection, and shock occurring very rapidly. Most cases of intussusception occur in children between five months and one year of age. Boys are affected three times more often than girls. The cause of intussusception is not known, although viral infections of the intestine may contribute to intussusception in infancy. In older children or adults, the presence of polyps or a tumor may trigger the intussusception. Early diagnosis is very important. Symptoms begin with sudden, loud crying in an infant, with the baby drawing the knees up to the chest while crying. This reaction is caused by abdominal cramping. The pain and crying is intermittent, but recurs frequently, and increases in intensity and duration. Fever is common. As the condition progresses, the infant becomes weak and then shows signs of shock, including pale color, lethargy, and sweating. About half of afflicted infants pass a bloody, mucousy ("currant jelly") stool. On examining the abdomen, the doctor may feel a mass. Abdominal X-rays may suggest intestinal obstruction, but a barium enema is needed to show the characteristic telescoping of the bowel.
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IPV: Inactivated polio vaccine. The polio virus in IPV has been inactivated (killed). The inactivated polio vaccine (IPV) is also called the Salk vaccine after the late American physician-virologist Jonas Salk.
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Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."
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Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.

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Liver disease: Liver disease refers to any disorder of the liver. The liver is a large organ in the upper right abdomen that aids in digestion and removes waste products from the blood.
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Lockjaw: See Tetanus .
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Measles : An acute and highly contagious viral disease characterized by fever , runny nose, cough, red eyes, and a spreading skin rash . Measles , also known as rubeola, is a potentially disastrous disease. It can be complicated by ear infections, pneumonia , encephalitis (which can cause convulsions, mental retardation, and even death), the sudden onset of low blood platelet levels with severe bleeding (acute thrombocytopenic purpura), or a chronic brain disease that occurs months to years after an attack of measles (subacute sclerosing panencephalitis).
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Meningitis: Inflammation of the meninges, usually due to a bacterial infection but sometimes from viral, protozoan, or other causes (in some cases the cause cannot be determined).
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Meningococcal vaccine : A vaccine to prevent meningococcal infection , including meningococcal meningitis , an inflammation of the membranes that cover the brain and spinal cord . Meningococcal infection is caused by the bacterium Neisseria meningitidis and can be fatal.
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MMR: Stands for the measles , mumps , rubella vaccine.
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Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.
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Mumps : An acute (sudden, shortlived) viral illness that usually presents with inflammation of the salivary glands, particularly the parotid glands. A child with mumps often looks like a chipmunk with a full mouth due to the swelling of the parotids (the salivary glands near the ears).
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Nasal: Having to do with the nose. Nasal drops are intended for the nose, not (for example) the eyes. The word "nasal" came from the Latin "nasus" meaning the nose or snout.
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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Paralysis: Loss of voluntary movement (motor function). Paralysis that affects only one muscle or limb is partial paralysis, also known as palsy; paralysis of all muscles is total paralysis, as may occur in cases of botulism .
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Pediatric: Pertaining to children.
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Pediatrics: "Pediatrics is concerned with the health of infants, children and adolescents, their growth and development, and their opportunity to achieve full potential as adults." (Richard E.Behrman in Nelson's Textbook of Pediatrics)
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Pertussis : Whooping cough, a communicable, potentially deadly illness characterized by fits of coughing followed by a noisy, "whooping" indrawn breath. It is caused by the bacteria Bordetella pertussis . The illness is most likely to affect young children, but sometimes appears in teenagers and adults, even those who have been previously immunized. Immunization with DPT (diphtheria-pertussis-tetanus) vaccine provides protection, although that immunity may wear off with age. When teenagers and adults get pertussis, it appears first as coughing spasms, and then a stubborn dry cough lasting up to eight weeks.
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Pharmacy: A location where prescription drugs are sold. A pharmacy is, by law, constantly supervised by a licensed pharmacist.
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Placebo: A "sugar pill" or any dummy medication or treatment.
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Pneumonia: Inflammation of one or both lungs with consolidation. Pneumonia is frequently but not always due to infection. The infection may be bacterial, viral, fungal or parasitic. Symptoms may include fever, chills, cough with sputum production, chest pain, and shortness of breath.
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Polio: Abbreviation for poliomyelitis, an acute and sometimes devastating disease caused by a virus. Man is the only natural host for polio virus. The virus enters the mouth and multiplies in lymphoid tissues in the throat and intestine. Small numbers of virus enter the blood and go to other sites where the virus multiplies more extensively. Another round of viremia (virus in the bloodstream) leads to invasion of the central nervous system (CNS), the spinal cord and brain, the target sites struck by the virus.
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Poliovirus: A member of the enterovirus subgroup, family Picornaviridae. Enteroviruses are transient inhabitants of the gastrointestinal tract . Picornaviruses are small viruses with an RNA genome. There are three strains of poliovirus. They are called P1 or the Brunhilde virus , P2 or the Lansing virus , and P3 or the Leon virus ). Immunity to one strain of poliovirus does not produce significant immunity to the other two strains. Poliovirus is rapidly inactivated by heat, formaldehyde , chlorine, or ultraviolet (UV) light.
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Precancerous: Pertaining to something that is not yet overtly cancerous, but appears to be on its way to becoming a cancer . Synonymous with premalignant.
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Primary: First or foremost in time or development. The primary teeth (the baby teeth) are those that come first. Primary may also refer to symptoms or a disease to which others are secondary.
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Public health: The approach to medicine that is concerned with the health of the community as a whole. Public health is community health. It has been said that: "Health care is vital to all of us some of the time, but public health is vital to all of us all of the time."
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Reye syndrome : A sudden, sometimes fatal, disease of the brain (encephalopathy) with degeneration of the liver, occurs in children (most cases 4-12 years of age), comes after the chickenpox (varicella) or an influenza-type illness, is also associated with taking medications containing aspirin.
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Rotavirus (RV): A leading cause of severe winter diarrhea in young children, RV each year causes an estimated 500,000 doctor visits and 50,000 hospital admissions in the United States. Almost everyone catches RV before entering school but, with rehydration (and good nutrition), nearly all recover fully. However, in poor countries it is estimated that there are at least 600,000 deaths of children under 5 years from RV diarrhea and dehydration .
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Sexually transmitted disease: Any disease transmitted by sexual contact; caused by microorganisms that survive on the skin or mucus membranes of the genital area; or transmitted via semen, vaginal secretions, or blood during intercourse. Because the genital areas provide a moist, warm environment that is especially conducive to the proliferation of bacteria, viruses, and yeasts, a great many diseases can be transmitted this way. They include AIDS, chlamydia, genital herpes, genital warts , gonorrhea, syphilis, yeast infections, and some forms of hepatitis. Also known as a morbus venereus or venereal disease.
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Sexually transmitted infection: An infection that can be transferred from one person to another through sexual contact. In this context, sexual contact is more than just sexual intercourse (vaginal and anal) and also includes kissing, oral-genital contact, and the use of sexual "toys," such as vibrators.
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Shock: In medicine, shock is a critical condition brought on by a sudden drop in blood flow through the body. There is failure of the circulatory system to maintain adequate blood flow. This sharply curtails the delivery of oxygen and nutrients to vital organs. It also compromises the kidney and so curtails the removal of wastes from the body. Shock can be due to a number of different mechanisms including not enough blood volume (hypovolemic shock) and not enough output of blood by the heart (cardiogenic shock). The signs and symptoms of shock include low blood pressure (hypotension), overbreathing (hyperventilation), a weak rapid pulse, cold clammy grayish-bluish (cyanotic) skin, decreased urine flow (oliguria), and mental changes (a sense of great anxiety and foreboding, confusion and, sometimes, combativeness).
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Skin: The skin is the body's outer covering. It protects us against heat and light, injury, and infection. It regulates body temperature and stores water, fat, and vitamin D. Weighing about 6 pounds, the skin is the body's largest organ. It is made up of two main layers; the outer epidermis and the inner dermis.

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Smallpox: Also known as variola, a highly contagious and frequently fatal viral disease characterized by a biphasic fever and a distinctive skin rash that left pock marks in its wake. Because of its high case-fatality rates and transmissibility, smallpox now represents a serious bioterrorist threat. The disease is caused by the variola virus. The incubation period is about 12 days (range: 7 to 17 days) following exposure. Initial symptoms include high fever, fatigue , and head and back aches. A characteristic rash, most prominent on the face, arms, and legs, follows in 2-3 days. The rash starts with flat red lesions that evolve at the same rate. Lesions become pus-filled and begin to crust early in the second week. Scabs develop and then separate and fall off after about 3-4 weeks.
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Spleen: An organ located in the upper left part of the abdomen near the stomach . The spleen produces lymphocytes ; it is the largest lymphatic organ in the body. The spleen also filters the blood, serves as a major reservoir for blood and destroys blood cells that are aged.
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STD: Sexually transmitted disease .
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Stool: The solid matter discharged in a bowel movement.
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Streptococcus: A group of bacteria, familiarly known as strep, that cause a multitude of diseases. The name comes from the Greek strepto- meaning twisted + kokkos meaning berry, and that is exactly what strep look like under the microscope, like a twisted bunch of little round berries. Illness caused by strep includes strep throat , strep pneumonia , scarlet fever, rheumatic fever (and rheumatic heart valve damage), glomerulonephritis, the skin disorder erysipelas, and PANDAS.
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Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
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Tetanus : An often fatal infectious disease caused by the bacteria Clostridium tetani (C. tetani) which usually enters the body through a puncture, cut, or open wound. Tetanus is characterized by profoundly painful spasms of muscles, including "locking" of the jaw so that the mouth cannot open (lockjaw). C. tetani releases a toxin that affects the motor nerves, (the nerves which stimulate the muscles).
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Toxicology: The study of the nature, effects and detection of poisons and the treatment of poisoning.
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Vaccination: Injection of a killed microbe in order to stimulate the immune system against the microbe, thereby preventing disease. Vaccinations, or immunizations , work by stimulating the immune system, the natural disease-fighting system of the body. The healthy immune system is able to recognize invading bacteria and viruses and produce substances (antibodies) to destroy or disable them. Immunizations prepare the immune system to ward off a disease. To immunize against viral diseases, the virus used in the vaccine has been weakened or killed. To only immunize against bacterial diseases, it is generally possible to use a small portion of the dead bacteria to stimulate the formation of antibodies against the whole bacteria. In addition to the initial immunization process, it has been found that the effectiveness of immunizations can be improved by periodic repeat injections or "boosters." Also see Vaccines (in the plural) and Vaccine of a specific type (such Vaccine, Polio).
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Vaccines: Microbial preparations of killed or modified microorganisms that can stimulate an immune response in the body to prevent future infection with similar microorganisms. These preparations are usually delivered by injection.
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Virus: A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell. A virus invades living cells and uses their chemical machinery to keep itself alive and to replicate itself. It may reproduce with fidelity or with errors (mutations)-this ability to mutate is responsible for the ability of some viruses to change slightly in each infected person, making treatment more difficult.
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Viruses: Small living particles that can infect cells and change how the cells function. Infection with a virus can cause a person to develop symptoms. The disease and symptoms that are caused depend on the type of virus and the type of cells that are infected.
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Whooping cough: Also known as pertussis , this is a feared infectious disease that can strike the respiratory system and affect other organs of the body. It has three stages-an initial stage with watery runny nose and eyes, a progressive cough stage with characteristic (sometimes severe) coughing spells, and (if the child survives) a recovery stage. The disease may last for 2-6 weeks. Therapy is supportive and many young infants need hospitalization if the coughing becomes severe. Immunization with DPT (diphtheria-pertussis-tetanus) vaccine provides protection. With pertussis, an ounce of prevention is worth a pound of cure (or, if you are metrically inclined, a gram of prevention is worth a kilo of cure). Have your child immunized!
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