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If indigestion is caused by excessive stomach acid, ulcers, GERD, esophagitis, or gastritis, a physician may prescribe potent acid blockers such as:
A combination of antibiotics and acid blockers may be prescribed for up to several months if the underlying cause is related to Helicobacter pylori (H. pylori).
If the underlying cause is found to be gastroparesis, pro-motility drugs such as metoclopramide (Reglan) may be prescribed.
If the underlying cause of indigestion is found to be related to depression or anxiety, antidepressants may be prescribed.
If the underlying cause is found to be a medication you are currently taking, do not abruptly stop the medication. Work with your physician to find alternatives that will not worsen your indigestion.
It the underlying cause is caused entirely or partially by lifestyle, medications listed above may help reduce symptoms, but changes in lifestyle (for example, less stress, and quitting smoking) will produce the best results (see prevention section below).
Medically Reviewed by a Doctor on 6/5/2014
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