Intrinsic Acute Renal Failure
Intrinsic or intrarenal acute renal failure (ARF) occurs when direct damage to the kidneys causes a sudden loss in kidney function. The treatment of intrinsic acute renal failure includes identifying and correcting the cause of the renal failure. The most common causes of intrinsic acute renal failure are acute tubular necrosis (ATN), acute glomerulonephritis (AGN), and acute interstitial nephritis (AIN).
Acute tubular necrosis (ATN)
Acute tubular necrosis (ATN) is a condition in which the small filtering tubes in the kidney are injured. ATN is a common cause of intrinsic acute renal failure often seen in people who are already hospitalized. ATN may occur because of:
Acute glomerulonephritis (AGN)
Glomerulonephritis is a condition in which the tiny blood vessels in the kidneys become inflamed and damaged. Damaged glomeruli do not filter blood properly.
Acute glomerulonephritis may be caused by an abnormal immune system response. Some specific conditions that cause acute glomerulonephritis include:
Acute interstitial nephritis (AIN)
Acute interstitial nephritis (AIN) is inflammation of the kidneys. It is usually caused by a medicine, such as an antibiotic or a nonsteroidal anti-inflammatory drug like aspirin or ibuprofen. But AIN may also be caused by a streptococcal, viral, or Legionella infection.
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