1. Irritable Bowel Syndrome (IBS) Slideshow Pictures
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Some drugs can trigger spasms of the colon and symptoms of IBS. These spasms can lead to constipation or diarrhea.

• Antibiotics, especially after prolonged use
  
  
• Antidepressants
  
  
• Medicine containing sorbitol, such as cough syrup

Prevention Strategies:

• Talk with your doctor about switching to a drug that won't worsen your IBS symptoms. Don't stop taking a drug without consulting with your doctor.
  
  
• If an antidepressant is worsening your diarrhea or constipation, talk with your doctor about switching medicine. Older antidepressants (called tricyclic antidepressants) can cause constipation. One type of newer antidepressant (called selective serotonin reuptake inhibitors, which include Prozac and Zoloft) can cause diarrhea. Your doctor can help you find an antidepressant that will not worsen your IBS symptoms.

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