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Lens-Particle Glaucoma (cont.)

Medical Treatment

Elevated IOP associated with lens-particle glaucoma often responds to treatment with medicated eye drops.

  • The preferred drugs for lowering IOP are usually aqueous suppressants, which are drugs that reduce the amount of fluid (aqueous humor) in the eye. Several types of aqueous-suppressant drugs are available. Topical beta-antagonists are typical first-line agents. Topical alpha-agonists and carbonic anhydrase inhibitors are usually considered adjunctive agents.


  • If lens-particle glaucoma is severe with sudden onset, hyperosmotic agents may be useful in quickly reducing and controlling IOP.


  • Prostaglandin analogs and miotics increase the outflow of fluid (aqueous humor) from the eye. Prostaglandin analogs have not been tested for lens-particle glaucoma, but they are not generally recommended because of the risk of increased intraocular inflammation. Likewise, miotic agents are usually not prescribed because they may worsen inflammation.
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Lens-particle glaucoma, a subclassification of lens-induced glaucoma,1, 2, 3, 4, 5 is a type of secondary open-angle glaucoma involving intraocular retention of fragmented lens debris.

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