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Leprosy Symptoms and Signs
The signs and symptoms of leprosy can vary depending on the individual's immune response to M. leprae. The WHO classification system uses clinical manifestations (the number of skin lesions and nerve involvement) as well as skin smear results to distinguish between forms of the disease. The two major WHO classifications are paucibacillary (PB) leprosy and multibacillary (MB) leprosy. However, within the WHO's simplified classification there can be a fairly wide range of patient presentations.
The Ridley-Jopling classification is another classification system that is used globally in evaluating patients in clinical studies and contains five different classifications of leprosy that further define the patient's severity of symptoms and disease progression. The six different categories, in order of increasing severity of disease, include indeterminate leprosy, tuberculoid leprosy, borderline tuberculoid leprosy, mid-borderline leprosy, borderline lepromatous leprosy, and lepromatous leprosy.
In general, the signs and symptoms of leprosy may vary with the form of the disease and include the following:
Medically Reviewed by a Doctor on 12/17/2015
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