Symptoms usually develop fairly quickly in acute leukemias. Most cases of acute leukemia are diagnosed when the person visits his or her healthcare provider after becoming ill. Symptoms develop gradually in chronic leukemias and are generally not as severe as in acute leukemias. About 20% of people with chronic leukemia do not have symptoms at the time their disease is diagnosed.
Some symptoms of leukemia are due to deficiencies of normal blood cells. Others are due to collections of leukemia cells in tissues and organs. Leukemia cells can collect in many different parts of the body, such as the testicles, brain, lymph nodes, liver, spleen, digestive tract, kidneys, lungs, eyes, and skin — in effect, virtually every tissue site.
The following symptoms of leukemia are common to all types:
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