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Liver Blood Tests (cont.)

Monitoring ALS and ALT Levels

Monitoring of the liver tests depends on the degree, the duration, and the cause of the abnormality. For example, in a person who has chronic (long standing) hepatitis B or C infection, the liver specialist (hepatologist) may opt for surveillance of these levels every 3 to 6 months to ensure that they are not rising.

On the other hand, if a healthy person is seen in the hospital for Tylenol overdose, then he or she needs to be monitored very closely, and ALT and ALT levels may be drawn a few times a day to monitor their trend and to guide therapy.

Other Liver Enzymes

There are several other liver enzymes performing important functions, however, many of these are not routinely measures in blood tests.

Alkaline phosphatase is very commonly reported with the transaminases as part of the metabolic panel blood test. This molecule typically resides in the wall of the intra- and extra-billiary ducts (tube-like structures within the liver that connect liver cells together and ultimately coalesce to from the bile duct, connecting the liver to the gallbladder). The elevation of this enzyme may indicate and injury or an inflammation to these tubes (ducts). Common causes for this are gallbladder obstruction and certain medications.

There are also other liver enzymes such as, lactate dehydrogenase (LDH), glutamate dehydrogenase, and gamma-glutamyltranspeptidase (GGT), which are less routinely measured clinically.

Reference: American Liver Foundation. Liver Function Tests. Jan14,2015.
< http://www.liverfoundation.org/abouttheliver/info/liverfunctiontests/>

Medically reviewed by Martin E Zipser, MD; American board of Surgery


Medically Reviewed by a Doctor on 8/19/2015

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